Results 71 to 80 of about 3,221,811 (296)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Divine and Human Action in Salvation in Augustine
, 2017 This chapter engages the work of Augustine on divine grace and human freedom in salvation. It works through the types of divine action seen in Augustine’s writings on grace in the Pelagian controversy as well as his work on baptism with respect to the ...
William J. Abraham
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Divine Action and the Meaning of Eternity
, 2018 In theological and philosophical analysis of divine eternity today there are debates about whether the notion of a ‘timeless’ or ‘atemporal’ God coheres with a Christian understanding of creation and divine action in time.
Steven J. Duby
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Benjamin and Spinoza: Divine Violence and Potentia
Eidos. A Journal for Philosophy of Culture, 2019 In this paper, I seek to clarify, criticize, and expand upon the ambiguous-yet-influential concept of divine violence introduced by Walter Benjamin’s “Zur Kritik der Gewalt”. I proceed in three parts: in the first, I outline Benjamin’s argument about the
Emerson R. Bodde
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
IS PHYSICS FUNDAMENTAL? ROBERT RUSSELL ON DIVINE ACTION
Zygon, 2010 Robert Russell's theological work has been a helpful stimulus to the task of understanding the meaning of divine action and providence in the age of science.
doaj +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Dissolution of Divine Action and Agency in Process Theology
, 2017 Recent philosophical work on divine action has been undertaken carefully and in a sustained manner by Process theologians. Thus the central aim of this chapter is to articulate and evaluate the salient options on offer with respect to divine action and ...
William J. Abraham
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source