Results 61 to 70 of about 144,792 (309)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Avicenna and Aquinas on the Negative Approach to the Attributes of God [PDF]

open access: yesحکمت اسرا, 2016
Negative approach to speaking of divine attributes is an age-old discussion and has two main categories: the negation and silence and the negative-positive way. The negative-positive way has various interpretations and meanings.
hasan abasi hasan Abadi
doaj  

Dawanī-Dashtakī Dispute on Divine Speech [PDF]

open access: yesپژوهشنامه فلسفه دین, 2018
The problem of divine speech, especially its nature, is one of the most challenging theological topics in the field of divine essence and attributes. Although the differences between philosophers and theologians are related to the temporal origination or
Mahmood Ahesteh
doaj   +1 more source

An Exposition of Augustine\u27s Theodicy: From Its Influences to Its Modern Application [PDF]

open access: yes, 2011
This paper delineates the thrust of Augustine\u27s theodicy against the broader background of his Christian Neoplatonic outlook. We examine Augustine\u27s initial Manichean influences and see how these beliefs carry over to his mature thought, which is ...
Gray, Kevin J.
core   +1 more source

The Relation between God and the World in the Pre-Critical Kant: Was Kant a Spinozist? [PDF]

open access: yes, 2016
Andrew Chignell and Omri Boehm have recently argued that Kant’s pre-Critical proof for the existence of God entails a Spinozistic conception of God and hence substance monism. The basis for this reading is the assumption common in the literature that God
Hoffer, Noam
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

DIALEKTIKA SIFAT DAN MAHIYAH TUHAN: Analisis Tahafut At-Tahafut Karya Ibnu Rusyd

open access: yesEl-Fikr
This study examines the dynamics of the debate concerning the divine attributes and mahiyah (essence) of God in Tahāfut al-Tahāfut by Ibn Rushd as a response to al-Ghazālī’s critique in Tahāfut al-Falāsifah. The research employs a descriptive-analytical
Afandi Nur Aziz Thohari
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

An analysis of god's attributes "The Beneficent" and "The Merciful" with regard to the philosophy of islamic jurisprudence [PDF]

open access: yes, 2003
I would like to begin my presentation with the quotation of the first sentence of Shafii’s Trea-tise er-Risala, the first work which has been reached us until now, concerning foundation of Islamic jurisprudence. “Praise be to God gratitude for one of His
Dagci, Samil
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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