Calcified atherosclerotic plaques inversely associated with plasma DKK1
openaire +3 more sources
Crystal structure of human Dickkopf 4 cysteine-rich domain 1 and evaluation of conformational rigidity. [PDF]
Shibata N.
europepmc +1 more source
Multi-Omics Characterization of Lactate-Associated Molecular Subtypes in Lung Cancer Suggests a Role for DKK1 in Lactate-Linked Migration, Invasion, and Lactylation Programs. [PDF]
Yu H +11 more
europepmc +1 more source
[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation. [PDF]
Hie M, Iitsuka N, Otsuka T, Tsukamoto I.
europepmc +1 more source
Comparative evaluation of dickkopf-1 levels in gingival crevicular fluid before and after nonsurgical therapy in type 2 diabetics and smokers with periodontal disease. [PDF]
Jayachandiran M +6 more
europepmc +1 more source
Multi-Omic and Spatial Profiling Identifies an Epithelial DKK1 Associated with Microenvironmental Remodeling in Pancreatic Ductal Adenocarcinoma. [PDF]
Xu J +6 more
europepmc +1 more source
Sclerostin and DKK1 in Primary Hyperparathyroidism
Bone formation is influenced by the Wnt pathway through effects on osteoblast functionality, and these actions are opposed by two antagonists: sclerostin and Dickkopf-1 (DKK1). Decreased levels of serum sclerostin were found after treatment with the PTH analogue teriparatide and in patients with primary hyperparathyroidism (PHPT), while treatment with ...
VIAPIANA, Ombretta +6 more
openaire +3 more sources
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DKK1 protein belongs to a family of inhibitors of the Wnt/beta1-catenin signaling pathway. Sporadic mutations affecting almost each major player of the Wnt/beta1-catenin pathway have been described in a variety of human carcinomas. DKK1 translation can be induced by p53, thereby linking TP53 and Wnt/beta1-catenin signaling pathways.
Sven Wellmann +2 more
exaly +3 more sources

