Results 191 to 200 of about 15,361 (230)

Case Report: A novel <i>DLL4</i> variant in a neonate with Adams-Oliver syndrome. [PDF]

Front Pediatr
Huang Y, Wang J, Zeng L, Wang S, Zhang X.   +4 more
europepmc   +1 more source

The involvement of exosomes in the tumorigenicity of breast cancer cell lines through the crosstalk between STAT3, Notch, and Wnt signaling pathways. [PDF]

Discov Oncol
Mohamed SA, Badawy TMI, Hussein MAMK, Salama M, El Kerm YM, Mohsen MAA.   +5 more
europepmc   +1 more source

Activated notch signaling pathway protects the intestinal barrier in DSS-induced colitis by regulating tight junctions. [PDF]

Eur J Med Res
Li T, Geng C, Li X, Song S, Li Y, Wang C.   +5 more
europepmc   +1 more source

Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling. [PDF]

Nat Commun
Gutierrez B, Liu TC, Rodriguez C, Pastor-Alonso O, Lambing H, Paredes MF, Flanagan LA.   +6 more
europepmc   +1 more source

Discovery of a pre-vein progenitor that requires VEGF/ERK inhibition to complete vein differentiation

Ang LT, Zheng SL, Liu KJ, Masaltseva A, Winters J, von Creytz I, Jha SK, Yin Q, Qian C, Xiong X, Dailamy A, Xi E, Alcocer JC, Sorensen DW, She R, Smolyar K, Szumska D, Nornes S, Martin RM, Lesch BJ, Restrepo NK, Sun W, Weissman JS, Lickert H, Porteus MH, Skylar-Scott MA, Mosimann C, Sumanas S, Val SD, Prescott JB, Red-Horse K, Loh KM.   +31 more
europepmc   +1 more source

BEST4/CA7⁺ and goblet cells are interdependent regulators of intestinal mucus homeostasis

Spoelstra WK, Wang D, van Es JH, Clevers H, van Zon JS, Tans SJ.   +5 more
europepmc   +1 more source

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Chronic DLL4 blockade induces vascular neoplasms

Nature, 2010
Delta-like 4 (DLL4)-mediated Notch signalling has emerged as an attractive target for cancer therapy. However, the potential side effects of blocking this pathway remain uncertain. Here we show that chronic DLL4 blockade causes pathological activation of endothelial cells, disrupts normal organ homeostasis and induces vascular tumours, raising ...
Minhong Yan
exaly   +3 more sources

Dll4 and Notch signalling couples sprouting angiogenesis and artery formation [PDF]

Nature Cell Biology, 2017
Endothelial sprouting and proliferation are tightly coordinated processes mediating the formation of new blood vessels during physiological and pathological angiogenesis. Endothelial tip cells lead sprouts and are thought to suppress tip-like behaviour in adjacent stalk endothelial cells by activating Notch.
Urs Hanno Langen, Takashi Nagasawa, Napoleone Ferrara   +2 more
exaly   +5 more sources