Results 91 to 100 of about 55,611 (129)
Disasters, Volume 49, Issue 3, July 2025.Abstract Despite the growth of disaster scholarship, the topic of how and why climate‐related disasters and extreme weather events vary among people with different types of disabilities remains unexplored. To help fill the gap, this study draws on a larger research project that was co‐designed by Water Sensitive Cities Australia at Monash University ...
Kien Nguyen‐Trung +7 more
wiley +1 more source
Clinical Pharmacology in Drug Development, Volume 14, Issue 6, Page 452-460, June 2025.Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre +3 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1803-1810, June 2025.Pediatric patients with advanced‐stage newly diagnosed Hodgkin lymphoma (HL) were treated with brentuximab vedotin (BV) combined with adriamycin, vinblastine, and dacarbazine (A + AVD). Weight‐based BV dosing is employed in adult patients, while both body weight‐ and body surface area (BSA)‐based dosing are used in pediatric patients.
Xiaofei Zhou +4 more
wiley +1 more source
Environmental Policy and Governance, Volume 35, Issue 3, Page 385-396, June 2025.Abstract Transformations of existing systemic structures are needed to address the root cause of many environmental land‐use (ELU) problems: unsustainable land use. One policy principle that can help achieve such transformation entails integrating cross‐cutting ELU problems with non‐environmental policy domains, also known as environmental policy ...
Mandy A. van den Ende +3 more
wiley +1 more source
eJHaem, Volume 6, Issue 3, June 2025.ABSTRACT Objective We report the results of a pilot study investigating the combination of brentuximab vedotin (BV) and lenalidomide in patients with relapsed/ refractory T‐cell lymphoma. Methods A dose escalation study design was utilized. Primary and secondary endpoints included maximum tolerated dose (MTD), adverse events, and response rates ...
Carrie van der Weyden +4 more
wiley +1 more source
Phase 2 Multi‐Arm Study of Magrolimab Combinations in Patients With Acute Myeloid Leukaemia
eJHaem, Volume 6, Issue 3, June 2025.ABSTRACT Introduction This phase 2 study evaluated magrolimab+venetoclax (VEN)+azacitidine (AZA) in untreated, unfit acute myeloid leukaemia (AML) and magrolimab+mitoxantrone+etoposide+cytarabine in relapsed/refractory (R/R) AML. Methods Endpoints included complete remission rate (CRR), overall response rate (ORR), overall survival (OS) and safety ...
Gabriel N. Mannis +17 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and although many patients respond to induction therapy, those who relapse or have refractory disease face a poor prognosis. Venetoclax has promising preclinical and clinical activity in ALL.
Andrew E. Place +21 more
wiley +1 more source
Policy &Internet, Volume 17, Issue 2, June 2025.ABSTRACT The article argues that the European Central Bank's (ECB) regulatory stance toward cryptocurrencies was underpinned by efforts to preserve legitimacy and monetary sovereignty. Triangulating a content analysis on the ECB's policy statements on cryptocurrencies, examination of European macroeconomic data, and price dynamic analysis of Bitcoin ...
Anson Au
wiley +1 more source
Cancer, Volume 131, Issue 10, 15 May 2025.Abstract Background The combination of anlotinib with chemotherapy has demonstrated encouraging efficacy in the treatment of nonsmall cell lung cancer (NSCLC). The objective of this phase 1/2 trial was to establish the maximum tolerated dose of anlotinib in combination with docetaxel and to assess the efficacy and safety of this regimen in patients ...
Jiawei Shou +11 more
wiley +1 more source
Distributed ledger technology (DLT) : introduction
, 2018 Distributed ledger technology is attracting the attention of the financial sector, both owing to its use in transactions with crypto-assets and to the proliferation of initiatives which have the potential to increase the efficiency, transparency, speed and resilience of processes underlying financial transactions.
openaire +1 more source