Obestatin Treatment Counteracts Muscle Wasting by Reactivation of Autophagy in Duchenne Muscular Dystrophy. [PDF]
Santos-Zas I +16 more
europepmc +1 more source
Structural Fiber Tract Alterations in Relation to Surgery in Children With a Posterior Fossa Tumor
Children that undergo posterior fossa tumor resection may experience post‐surgery neurological symptoms related to disruption of the dentato‐rubro‐thalamic tract (DRTT). By comparing pre‐ and intraoperative diffusion MRI tractography, we observed more variation in microstructural measures in the DRTT near the resection cavity, which were more ...
Pien E. J. Jellema +7 more
wiley +1 more source
Scanning-Based Dynamic Mask Projection for Ultrafast Laser Ablation of Thin Films. [PDF]
Amann J +6 more
europepmc +1 more source
Abstract Alpha‐synuclein (αSyn) is a presynaptic protein associated with several neurodegenerative diseases. While the non‐amyloid component (NAC) region of the αSyn sequence (residues 65–90) forms the core of all αSyn fibrils, recent findings suggest that the flanking regions play a key role in initiating or preventing amyloid formation. Two motifs in
Van T. T. Nguyen +4 more
wiley +1 more source
Direct AMPK Activation Confers Mutation-Independent Therapeutic Benefit in Duchenne Muscular Dystrophy. [PDF]
Ng SY +12 more
europepmc +1 more source
Arianna's Palette: A Diagnostic Study of the Painting Walls of the Domus of Arianna in Pompeii
ABSTRACT The House of Arianna, also known as the House of Colored Capitals, represents, with its 1700 m2 of floor space, one of the most majestic examples of a residence within the Pompeii archaeological site. The research developed within the project “Cultural Heritage Active Innovation for Sustainable Society—CHANGES” reports the outcomes of the ...
Maria Verde +9 more
wiley +1 more source
Caregiver burden in Duchenne muscular dystrophy in Europe, Japan, and the United States - a real-world study. [PDF]
Strober J +11 more
europepmc +1 more source
Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley +1 more source
Disease exacerbation in human DMD MYOrganoids enables gene therapy evaluation and unveils persistence of fibrotic activity. [PDF]
Palmieri L +12 more
europepmc +1 more source
Two‐photon lithography (TPL) enables 3D magnetic nanostructures with unmatched freedom in geometry and material choice. Advances in voxel control, deposition, and functionalization open pathways to artificial spin ices, racetracks, microrobots, and a number of additional technological applications.
Joseph Askey +5 more
wiley +1 more source

