Results 71 to 80 of about 866,260 (307)

Sulphur compounds, methane, and phytoplankton: interactions along a north–south transit in the western Pacific Ocean [PDF]

Biogeosciences, 2013
Here we present results of the first comprehensive study of sulphur compounds and methane in the oligotrophic tropical western Pacific Ocean. The concentrations of dimethylsuphide (DMS), dimethylsulphoniopropionate (DMSP), dimethylsulphoxide (DMSO), and ...
C. Zindler, A. Bracher, C. A. Marandino, B. Taylor, E. Torrecilla, A. Kock, H. W. Bange   +6 more
doaj   +1 more source

Raman Spectroscopic and Computational Analysis of the Effects of Noncovalent Interactions on DMSO [PDF]

, 2014
Dimethyl sulfoxide (DMSO) is a widely used chemical in synthetic chemistry and also has unique and important biological applications. In the pure liquid, DMSO forms chain like structures of alternating sulfur and oxygen atoms due to its high self ...
Nicholson, Ashton T.
core   +1 more source

Palladium-Catalyzed Cascade Approach to 12-(Aryl)indolo[1,2- c ]quin­azolin-6(5 H )-ones [PDF]

, 2018
A straightforward one-pot approach to the synthesis of challenging 12-arylindolo[1,2-c]quinazolin-6(5H)-ones is described. Starting from readily available o-(o-aminophenylethynyl)trifluoroacetanilides, palladium-catalyzed aminoarylation of the triple ...
Arcadi, Antonio, Cacchi, Sandro, Fabrizi, Giancarlo, Ghirga, Francesca, Goggiamani, Antonella, Iazzetti, Antonia, Marinelli, Fabio   +6 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Effect of perphenazine and prochlorperazine on viability of human astrocytes

Annales Academiae Medicae Silesiensis
Phenothiazine derivatives are well-known anti-psychotic drugs that possess several biological activities including anticancer activity. Much research provides data about its anticancer activity against human glioblastoma cell lines.
Michał Otręba, Anna Rzepecka-Stojko, Jerzy Stojko, Agata Kabała-Dzik, Anna Kleczka   +4 more
doaj   +1 more source

UV-B induced alteration of oxygen evolving reactions in pea thylakoid membranes as affected by scavengers of reactive oxygen species

Biologia Plantarum, 2014
The effect of UV-B irradiation at temperatures of 22 and 4 °C on flash induced oxygen yields, photochemical activity, and energy transfer in pea thylakoid membranes in the absence and presence of scavengers of reactive oxygen species (ROS) was studied ...
D. Lazarova, D. Stanoeva, A. Popova, D. Vasilev, M. Velitchkova   +4 more
doaj   +1 more source

17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle [PDF]

, 2016
Rationale & Aim: Estrogen and estrogen-mediated signalling protect from hepatitis C virus through incompletely understood mechanisms. We aimed to ascertain which phase(s) of HCV life cycle is/are affected by estrogens.
Barbaglia, Matteo N., Boccato, Elisa, Burlone, Michela E., Cole, Sarah, Foglia, Chiara Z., Giarda, Paola, Grossini, Elena, Magri, Andrea, Minisini, Rosalba, Patel, Arvind H., Pirisi, Mario   +10 more
core   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Criopreservación de la cepa RH de Toxoplasma gondii utilizando como criopreservante DMSO y glicerol

Revista Científica Ciencias de la Salud, 2019
El trabajo tuvo como objetivo evaluar la viabilidad de parásitosde Toxoplasma gondiide la cepa RH criopreservados en nitrógeno líquido durante 1 y 5 meses con dos criopreservantes: el glicerol 10% y dimetilsulfóxido (DMSO) 1,25%, 12,5% y 25%,
Carmen Ozuna, Alejandra Rojas, Laura Arias, Teresa Meza, Ivalena Guillén, María Eugenia Acosta   +5 more
doaj  

Aromatic N versus aromatic F : bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs [PDF]

, 2010
The thermodynamics of base pairing is of fundamental importance. Fluorinated base analogs are valuable tools for investigating pairing interactions. To understand the influence of direct base–base interactions in relation to the role of water, pairing ...
Alrun N. Koller, Jelena Božilović, Joachim W. Engels, Holger Gohlke, Schweitzer, Loakes, Parsch, Lai, Somoza, Murray-Rust, Dunitz, Dunitz, Kool, O'H, Olsen, Olsen, Olsen, Müller, Thalladi, Desiraju, Reichenbächer, Kopitz, Turner, Stofer, Freier, Turner, Tanner, Kierzek, Vesnaver, Levitt, Arora, Cubero, Meyer, Ryjácek, Cubero, Florian, Bats, Živković, Klöpffer, Živković, Bégué, Bayly, Cornell, Müller, Torrie, Case, Šponer, Šponer, Šponer, Jorgensen, Berendsen, Ryckaert, Darden, Bouzida, Efron, MacCallum, Varani, Buckin, Gao, Kool, Šponer, Barsky, Zacharias, Ran, Smart, Jeffrey, Bondi, Hof, Jakobi, Eritja, Parsch, Vorbrüggen, Furneaux, Rolland, Guckian   +74 more
core   +1 more source