Results 71 to 80 of about 35,348 (219)

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

The FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe, Ricardo Alva, Fereshteh Moradi, Sarah Alderman, Ping Liang, Jeffrey A. Stuart   +5 more
wiley   +1 more source

Study on sperm cryopreservation of hybrid fish derived from Carassius cuvieri (♀) × Carassius auratus red var (♂)

Reproduction and Breeding
Cryopreservation of sperm is an effective method for conserving germplasm resources in fish genetic breeding. The high-quality hybrid fish (WR) derived from white crucian carp (Carassius cuvieri, WCC, ♀) and red crucian carp (C. auratus red var., RCC, ♂),
Qianqian Zeng, Yixuan Chen, Minyi Wang, Yinggang Li, Tao Dai, Weiling Qin, Yating Zhu, Chun Zhang, Yi Zhou, Qinbo Qin, Conghui Yang, Qianhong Gu   +11 more
doaj   +1 more source

A chemo‐enzymatic colorimetric cascade for detecting ethylene glycol contamination

The FEBS Journal, EarlyView.
A chemo‐enzymatic cascade is developed for ethylene glycol (EG) detection. EG is oxidized by GoADH with C1‐mediated cofactor recycling to produce glycolaldehyde (GAL). GAL subsequently reacts with purpald to generate a detectable purple chromophore.
Tawatchai Singphongam, Tadtarit Anujareewat, Wachirawit Chinantuya, Pratchaya Watthaisong, Chayasith Uttamapinant, Somchart Maenpuen, Ruchanok Tinikul   +6 more
wiley   +1 more source

Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund’s Adjuvant-Induced Mono-Arthritis

Molecules, 2018
Rheumatoid arthritis (RA) is characterized by inflammation of one or more joints, and affects ~1% of the adult population worldwide. Sulforaphane (SFN) is a natural compound that has been suggested as an antioxidant.
João Francisco Silva Rodrigues, Cristiane Silva e Silva, Thayanne França Muniz, Alana Fernanda de Aquino, Larissa Neuza da Silva Nina, Nagila Caroline Fialho Sousa, Luis Claudio Nascimento da Silva, Breno Glaessner Gomes Fernandes de Souza, Tatiana Aranha da Penha, Ana Lúcia Abreu-Silva, Joicy Cortez de Sá, Elizabeth Soares Fernandes, Marcos Augusto Grigolin Grisotto   +12 more
doaj   +1 more source

Coniferyl aldehyde from the phenylpropanoid pathway targets pyruvate kinase in Dactylobotrys graminicola to confer sheath rot resistance in hulless barley

Journal of Integrative Plant Biology, EarlyView.
Hulless barley resists the newly identified sheath rot disease caused by the necrotrophic fungal pathogen Dactylobotrys graminicola by releasing coniferyl aldehyde, a natural compound that disrupts energy production in the fungus. ABSTRACT Dactylobotrys graminicola (Dgr), a necrotrophic fungal pathogen, has recently been identified as the causative ...
Haowen Zheng, Liyifan Chen, Jianguo Wei, Yuandi Xu, Rangrang Chen, Yu Li, Yan Liu, Jiahui Yan, Lu Hou, Yiliang Chen, Zhensheng Kang, Haifeng Zhang, Qiang Yao   +12 more
wiley   +1 more source

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

Molecular Microbiology, EarlyView.
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol, Dominik Šťastný, J. Pedro Fernandez‐Murray, Christopher R. McMaster, Peter Griač, Dave Richard   +5 more
wiley   +1 more source

The effect of lovastatin on cognition impairment induced by bilateral electrical lesion of nucleus basalis magnocellularis in the Alzheimer’s disease model in adult male rats

Fiyz̤, 2017
Background: Statins, inhibitors of 3-hydroxy-3-methyl glutaryl coenzyme A reductase, are widely used as medication to lower cholesterol levels in human patients. Much evidence indicates that statins can also exert neuroprotective actions.
Azade Eskandary, Ahmad Ali Moazedi , Hossein Najaph Zade Varzi, Firoz Ghadery Pakdel , Mohammad Reza Akhond   +4 more
doaj  

Paving the Way for Plant‐Based Bioproduction of (Z)‐13‐Octadecenoic Moth Pheromone Compounds

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sex pheromones are eco‐friendly agents to control pest insects. Yet, the cost of synthetic pheromone production has restricted their use essentially to high value crops. Plant‐based bioproduction of pheromone compounds offers a promising and sustainable alternative, opening up for the deployment of pheromone‐mediated pest control also in row ...
Mengyu Liu, Huijing Li, Huanhuan Jin, Yue Xiao, Panpan He, Chang Tan, Hong‐Lei Wang, Jean‐Marc Lassance, Christer Löfstedt, Bao‐Jian Ding   +9 more
wiley   +1 more source

Impact of Aflatoxin B1 on hematological indices, oxidative stress, and gill surface ultrastructure in Channa punctata

Journal of Basic and Applied Zoology
Background Aflatoxin contamination is a global concern that imperils food security and aquaculture. This study was focused on evaluating the toxicological impact of Aflatoxin B1 on fish growth, hematological parameters, and oxidative stress markers in ...
Gazee Owais Yousuf, Umaiya Farooq, Nikhil Maheshwari, Madhu Gupta, Md Arshad   +4 more
doaj   +1 more source

Beyond anaerobic respiration—new physiological roles for DmsABC and other S-/N-oxide reductases in Escherichia coli

Journal of Bacteriology
Sulfoxide reductases in pathogenic bacteria have recently received increasing attention for their association with virulence and survival within the host.
Qifeng Zhong, Marufa Nasreen, Ruizhe Yang, Michel Struwe, Bostjan Kobe, Ulrike Kappler   +5 more
doaj   +1 more source