Results 111 to 120 of about 87,328 (317)

Modelling Dimethoate Removal by Fenton-Like Process Using Response Surface Methodology

open access: yesProceedings, 2018
The (RSM) is a useful method for optimizing analytical methods and it has been applied to evaluate independent variables in FPs. In this study, the removal of dimethoate (DMT) which is a commonly used pesticide and has a toxic effect on the environment ...
Berrak Erol Nalbur   +3 more
doaj   +1 more source

Exploratory study of the dose-related safety, tolerability, and efficacy of dimethyltryptamine (DMT) in healthy volunteers and major depressive disorder

open access: yesNeuropsychopharmacology, 2022
D. D’Souza   +5 more
semanticscholar   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

open access: yesAdvanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang   +21 more
wiley   +1 more source

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

open access: yesAngewandte Chemie, EarlyView.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

A dance movement therapy group for depressed adult patients in psychiatric outpatient clinic: Effects of the treatment

open access: yesFrontiers in Psychology, 2015
We were interested in investigating the effects of dance movement therapy (DMT) in a psychiatric outpatient clinic with patients diagnosed with depression.
Päivi Maria Pylvänäinen   +3 more
doaj   +1 more source

5-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in mice

open access: yesNeuropsychopharmacology, 2023
S. Jefferson   +10 more
semanticscholar   +1 more source

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

open access: yesAdvanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu   +5 more
wiley   +1 more source

DMT micro-phenomenology

open access: yes
DMT reliably induces profound experiences of immersion in other worlds and encounters with seemingly autonomous presences, yet the lived qualities and unfolding of these experiences remain poorly understood. Using micro-phenomenological interviews with twenty-three healthy participants who received DMT during fMRI scanning, this study explores how ...
James W. Sanders   +4 more
openaire   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

open access: yesAdvanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang   +8 more
wiley   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

open access: yesAdvanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen   +10 more
wiley   +1 more source

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