Results 121 to 130 of about 3,049,090 (315)

Microbial DNA fingerprinting of human fingerprints: dynamic colonization of fingertip microflora challenges human host inferences for forensic purposes [PDF]

, 2009
Human fingertip microflora is transferred to touched objects and may provide forensically relevant information on individual hosts, such as on geographic origins, if endogenous microbial skin species/strains would be retrievable from physical ...
Wamel, W.J.B. (Willem) van, Belkum, A., van, Belkum, Alex, Tims, S. (Sebastian), Sebastian Tims, Willem van Wamel, Belkum, A.F. (Alex) van, Kayser, M.H. (Manfred), Tims, S., Endtz, H.P., Endtz, Hubert, Tims, S (Sebastian), Endtz, H.P. (Hubert), Kayser, M., Manfred Kayser, van Belkum, A., van Wamel, Willem, Wamel, W., van, van Wamel, W., Hubert P. Endtz, van Wamel, Willem; id_orcid, Kayser, Manfred, Alex van Belkum   +22 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei [PDF]

, 1992
Tissue-specific patterns of methylated deoxycytidine residues in the mammalian genome are preserved by postreplicative methylation of newly synthesized DNA. DNA methyltransferase (MTase) is here shown to associate with replication foci during S phase but
Heinz-Ulrich Weier, Page, A.W., Weier, H.U., Andrea W. Page, Bestor, Timothy H., Bestor, T. H., Heinrich Leonhardt, Page, A. W., Page, Andrea W., Leonhardt, Heinrich, Weier, H. U., Weier, Heinz-Ulrich, Bestor, T.H., Timothy H. Bestor, Leonhardt, H.   +14 more
core   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Correlation between Protection against Sepsis by Probiotic Therapy and Stimulation of a Novel Bacterial Phylotype [PDF]

, 2011
Item does not contain fulltextProphylactic probiotic therapy has shown beneficial effects in an experimental rat model for acute pancreatitis on the health status of the animals.
Smidt, H., Gooszen, H.G., Rijkers, G.T., Minnen, L.P. van, van Minnen, L.P., Fuentes, S., Akkermans, L.M., Hauke Smidt, Minnen, L.P., van, Frans M. Rombouts, Gerritsen, J., Ger T. Rijkers, Susana Fuentes, Jacoline Gerritsen, Konstantinov, S.R., Akkermans, L.M.A., Rombouts, F.M., Panneman, H., Harro M. Timmerman, Henk Panneman, Louis M. A. Akkermans, L. Paul van Minnen, Hein G. Gooszen, Timmerman, H.M., Sergey R. Konstantinov   +24 more
core   +1 more source

Use of the checkerboard DNA-DNA hybridization technique for bacteria detection in Aedes aegypti (Diptera:Culicidae) (L.)

Parasites & Vectors, 2011
Background Bacteria associated with insects can have a substantial impact on the biology and life cycle of their host. The checkerboard DNA-DNA hybridization technique is a semi-quantitative technique that has been previously employed in odontology to ...
Gaio Analiz de Oliveira, Rodrigues Rivea CC, do Nascimento Cássio, Secundino Nagila FC, Lemos Francisco JA, Pimenta Paulo FP, Monesi Nadia   +6 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Development of real-time PCR for detection of Mycoplasma hominis [PDF]

, 2004
Background: Mycoplasma hominis is associated with pelvic inflammatory disease, bacterial vaginosis, post partum fever, sepsis and infections of the central nervous system often leading to serious conditions.
Christiansen, G, Fedder Jens, Birkelund, S., Christiansen Gunna, Gunna Christiansen, Fedder, J., Christiansen, G., Svenstrup, HF, Svenstrup Helle F, Baczynska Agata, Helle F Svenstrup, Baczynska, A, Fedder, J, Birkelund Svend, Baczynska, A., Svendstrup, H.F., Agata Baczynska, Jens Fedder, Svend Birkelund, Birkelund, S   +19 more
core   +1 more source

Regulatory Landscapes of Bacterial DNA Methylation: Mechanism, Dynamics, and Detection

DNA
Epigenetics is a widely present mechanism for the modulation of gene expression without alterations in the underlying genetic sequence. Epigenetic signatures are significantly present in bacteria, with DNA methylation playing a key role in the modulation
Jasleen Kaur Lamba, Tejinder Kaur, Roshani Jha, Rama Kadamb, Rajni Garg   +4 more
doaj   +1 more source

Intravesicle Isothermal DNA Replication

BMC Research Notes, 2011
Background Bacterial and viral DNA replication was previously reconstituted in vitro from component parts 1234. Significant advances in building minimal cell-like structures also have been made recently 567.
Ross Lindsey A, Del Bianco Cristina, Torino Domenica, Ong Jennifer L, Mansy Sheref S   +4 more
doaj   +1 more source