Results 111 to 120 of about 3,049,090 (315)

High-throughput sequencing of 16S rRNA gene amplicons : effects of extraction procedure, primer length and annealing temperature [PDF]

, 2012
The analysis of 16S-rDNA sequences to assess the bacterial community composition of a sample is a widely used technique that has increased with the advent of high throughput sequencing.
Sergeant Martin J., Penn, Charles W, Cogan Tristan, Pallen, Mark J., Charles W Penn, Chrystala Constantinidou (161352), Charles W. Penn (161371), Sergeant, MJ, Cogan, Tristan, Tristan Cogan (161360), Constantinidou Chrystala, Constantinido, C, Mark J Pallen, Tristan Cogan, Martin J. Sergeant (161344), Constantinidou, Chrystala, Sergeant, Martin J, Penn Charles W., Pallen, Mark J, Sergeant, Martin J., Chrystala Constantinidou, Mark J. Pallen (8904), Penn, CW, Pallen, MJ, Penn, Charles W., Pallen Mark J., Martin J Sergeant, Cogan, TA   +27 more
core   +2 more sources

Author Correction: Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity. [PDF]

Commun Biol, 2021
Huang Q, Li R, Yi T, Cong F, Wang D, Deng Z, Zhao YL.   +6 more
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

The DNA Binding Protein Lsr2 from Mycobacterium tuberculosis [PDF]

, 2012
Lsr2 is a small, basic DNA binding protein that is highly conserved in mycobacteria and related actinomycetes. Lsr2 is essential for growth in Mycobacterium tuberculosis and previous studies have shown that Lsr2 is involved in down-regulating a wide ...
Summers, Emma Louise
core  

The Structure of the Oligomerization Domain of Lsr2 from Mycobacterium tuberculosis Reveals a Mechanism for Chromosome Organization and Protection [PDF]

, 2012
Lsr2 is a small DNA-binding protein present in mycobacteria and related actinobacteria that regulates gene expression and influences the organization of bacterial chromatin.
Isabel Usón (319527), Kathrin Meindl, Isabel Usón, Usón Isabel, Arcus Vickery L., David Alland, Radjainia Mazdak, David Alland (31640), Alland, David, Radjainia, Mazdak, Summers, Emma Louise, Vickery L. Arcus (319529), Roberto Colangeli, Alland David, Mazdak Radjainia, Mitra Alok K., Kathrin Meindl (319526), Emma L. Summers (319525), Alok K. Mitra (206395), Roberto Colangeli (31628), Colangeli Roberto, Colangeli, Roberto, Emma L Summers, Meindl, Kathrin, Vickery L Arcus, Summers Emma L., Mazdak Radjainia (319528), Alok K Mitra, Summers, Emma L., Mitra, Alok K., Meindl Kathrin, Arcus, Vickery L., Usón, Isabel   +32 more
core   +2 more sources

Recognition of a tandem lesion by DNA bacterial formamidopyrimidine glycosylases explored combining molecular dynamics and machine learning. [PDF]

Comput Struct Biotechnol J, 2021
Bignon E, Gillet N, Chan CH, Jiang T, Monari A, Dumont E.   +5 more
europepmc   +1 more source

Large-scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome

Nature Communications
Transducing bacteriophage and gene transfer agents (GTAs) are constrained by the structural limits of their capsids, which determine the maximum length of host DNA they can package.
Tatiana Borodovich, Colin Buttimer, Jason S. Wilson, Pavol Bardy, Muireann Smith, Conor Hill, Ekaterina V. Khokhlova, Matthew Harte, Bianca Govi, Paul C. M. Fogg, Colin Hill, Andrey N. Shkoporov   +11 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. [PDF]

, 2008
BACKGROUND: Human and animal health is constantly under threat by emerging pathogens that have recently acquired genetic determinants that enhance their survival, transmissibility and virulence.
Oyston, Petra C. F., Titball, Richard W., Hinds, Jason, Richard W Titball, Wren, Brendan W, Dawson, LF, Titball Richard W, Dawson Lisa F, Lisa F Dawson, Richard A Stabler, Wren, Brendan W., Oyston, Petra CF, Titball, RW, Stabler, Richard A, Dawson, Lisa F, Dawson, Lisa F., Hinds Jason, Oyston, PCF, Stabler, Richard A., Stabler Richard A, Wren, BW, Witney, AA, Petra CF Oyston, Titball, Richard W, Oyston Petra CF, Witney, Adam A, Jim Wade, Witney Adam A, Witney, Adam A., Hinds, J, Wren Brendan W, Wade, Jim, Jason Hinds, Wade, J, Stabler, RA, Oyston, PC, Adam A Witney, Wade Jim, Brendan W Wren   +38 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source