Results 261 to 270 of about 4,244,193 (328)

Bacterial‐Based Molecular Communication: Simulation of a Fixed and Receding Receiver Scenarios in Varied Viscosities and Environmental Conditions

Advanced Theory and Simulations, EarlyView.
This study presents a robust 3D simulation for BBMC, focusing on both fixed and receding receiver scenarios across various conditions. Key parameters such as D, Q, u, and d are tested at different values to assess the performance and reliability of BBMC in applications like drug delivery, addressing critical challenges in nanoscale communication with ...
Mustafa Ozan Duman, Ibrahim Isik, Esme Isik, Mehmet Bilal Er   +3 more
wiley   +1 more source

Benchmarking 16S rRNA Gene-Based Approaches to Bacterial Taxonomy Assignment Based on Amplicon Sequencing With Illumina and Oxford Nanopore. [PDF]

Int J Microbiol
Hoffbeck C, Middleton DMRL, Nelson NJ, Taylor MW.   +3 more
europepmc   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Optimization of heat inactivation protocols for Orientia and Rickettsia species. [PDF]

Sci Rep
Rungrojn A, Abdad MY, Dhawan S, Wongsantichon J, Blacksell SD.   +4 more
europepmc   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

Temperature-Sensitive Lipids Reveal Intraspecific Diversity in Bacteria Isolated from an Ancient Antarctic Microbial Mat. [PDF]

Microb Ecol
Lezcano MÁ, Carrizo D, Lominchar MÁ, Sánchez-García L, Quesada A, Parro V.   +5 more
europepmc   +1 more source

Succinate Dehydrogenase Subunit A (SDHA) Mediated Microglia Extracellular Traps Formation Participating in Cerebral Ischemic Reperfusion Injury

Advanced Science, EarlyView.
This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao, Tao Li, Meijuan Dang, Ye Li, Jialiang Lu, Ziwei Lu, Zhiyang Chen, Qiao Huang, Yujie Chen, Yang Yang, Yuxuan Feng, Xiaoya Wang, Yating Jian, Heying Wang, Yingying Guo, Lei Zhang, Yu Jiang, Songhua Fan, Shengxi Wu, Hong Fan, Fang Kuang, Guilian Zhang   +21 more
wiley   +1 more source

The cystic fibrosis pathogen <i>Achromobacter xylosoxidans</i> inhibits biofilm formation of <i>Pseudomonas aeruginosa</i>. [PDF]

J Med Microbiol
Sahl C, Andersson A, Larsson N, Paulsson M, Shannon O, Påhlman LI.   +5 more
europepmc   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

UltraCAST: A Flexible All-In-One Suicide Vector for Modifying Bacterial Genomes Using a CRISPR-Associated Transposon. [PDF]

MicroPubl Biol
VanDieren AJ, Barrick JE.
europepmc   +1 more source