Results 71 to 80 of about 428,487 (304)

Tricarbonyl M(I) (M = Re, 99mTc) complexes bearing acridine fluorophores : synthesis, characterization, DNA interaction studies and nuclear targeting [PDF]

, 2010
© The Royal Society of Chemistry 2010New pyrazolyl-diamine ligands with acridine derivatives at the 4-position of the pyrazolyl ring were synthesized and characterized (L1 and L2).
Agorastos, Alves, António Paulo, Bowler, Buchegger, Cai1, Catarina Xavier, Drews, Fernanda Marques, Filipa Mendes, Fredericq, Giampietro Viola, Ginj, Ginj, Hofer, Häfliger, Isabel Santos, José Rino, João Costa Pessoa, Kapuscinski, Karamychev, Kumar, Kumar, Kure, Kuruvilla, Lazarova, Lloyd, Lyles, Marques, McGhee, Moura, Norden, Paula D. Raposinho, Rodger, Santos, Sofia Gama, Teresa Esteves, Troutner, Vitor, Vitor, Wada, Zimmermann   +41 more
core   +1 more source

Entropic penalties in circular DNA assembly [PDF]

The Journal of Chemical Physics, 2014
The thermodynamic properties of DNA circular molecules are investigated by a new path integral computational method which treats in the real space the fundamental forces stabilizing the molecule. The base pair and stacking contributions to the classical action are evaluated separately by simulating a broad ensemble of twisted conformations.
openaire   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells [PDF]

, 2016
Extrachromosomal circular DNAs (eccDNAs) are common genetic elements in Saccharomyces cerevisiae and are reported in other eukaryotes as well. EccDNAs contribute to genetic variation among somatic cells in multicellular organisms and to evolution of ...
Bojsen, Rasmus Kenneth, Botstein, David, Møller, Henrik D., Parsons, Lance, Regenberg, Birgitte, Tachibana, Chris   +5 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Virological and morphological relationships in the phases of the immune control and reactivation in patients with chronic hepatitis B

Журнал инфектологии, 2016
Objective: To evaluate relationships between virological and morphological data in patients with chronic hepatitis B in phase immune control and reactivation.Materials and methods: The study involved 46 patients with chronic hepatitis B, indicators ...
I. A. Gabdrakhmanov, A. V. Semenov, Yu. V. Ostankova, K. V. Kozlov, K. V. Zhdanov, D. A. Gusev, V. S. Sukachev, D. M. Shakhmanov, S. S. Zhabrov, A. S. Peremyshlenko, Yu. I. Bulankov, A. M. Ivanov, A. A. Totolian   +12 more
doaj   +1 more source

Sequence organization of feline leukemis virus DNA in infected cells [PDF]

, 1980
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W., Davidson, Norman, Mullins, James I., Nicolson, Margery O.   +3 more
core   +1 more source

Total positive curvature of circular DNA [PDF]

Physical Review E, 2013
The properties of double-stranded DNA and other chiral molecules depend on the local geometry, i.e., on curvature and torsion, yet the paths of closed chain molecules are globally restricted by topology. When both of these characteristics are to be incorporated in the description of circular chain molecules, e.g., plasmids, it is shown to have ...
Bohr, Jakob, Olsen, Kasper Wibeck
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Study of In vitro antioxidant and DNA damage protection activity of a novel luteolin derivative isolated from Terminalia chebula

Journal of Taibah University for Science, 2019
The present study aimed to investigate the efficacy of flavonoids isolated from the fruit of Terminalia chebula against the hydrogen peroxide-induced DNA damage.
K. Soumya, Karickal R. Haridas, Jesna James, V. B. Sameer Kumar, Lincy Edatt, S. Sudheesh   +5 more
doaj   +1 more source