Results 1 to 10 of about 797,307 (281)

Novel codons in rat Pdx-1 complementary DNA [PDF]

BMC Research Notes, 2018
Objectives Pancreatic and duodenal homeobox-1 (Pdx-1) is a homeodomain-containing transcription factor essential for pancreatic development, beta-cell differentiation and the maintenance of mature beta cell function.
Takayoshi Kiba
doaj   +3 more sources

Rapid and Sensitive Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Label-Free Manner Using Micromechanical Sensors

Sensors, 2021
Coronavirus (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been identified as a deadly pandemic. The genomic analysis of SARS-CoV-2 is performed using a reverse transcription-polymerase chain reaction (RT-PCR)
Dalal A. Aloraini, Aljawhara H. Almuqrin, Amal Alanazi, Qura Tul Ain, Abdullah N. Alodhayb   +4 more
doaj   +1 more source

A Brief Review of Graphene-Based Biosensors Developed for Rapid Detection of COVID-19 Biomarkers

Biosensors, 2023
The prevalence of mutated species of COVID-19 antigens has provided a strong impetus for identifying a cost-effective, rapid and facile strategy for identifying the viral loads in public places.
Narendhar Chandrasekar, Ramachandran Balaji, Ramaswamy Sandeep Perala, Nik Zulkarnine Nik Humaidi, Kirubanandan Shanmugam, Ying-Chih Liao, Michael Taeyoung Hwang, Saravanan Govindaraju   +7 more
doaj   +1 more source

Synthesis and Evaluation of MGB Polyamide-Oligonucleotide Conjugates as Gene Expression Control Compounds

Journal of Nucleic Acids, 2023
MGB polyamide-oligonucleotide conjugates ON 1-4 with linked MGB polyamides at the 2-exocyclic amino group of a guanine base using aminoalkyl linkers were synthesized and evaluated in terms of binding affinity for complementary DNA containing the MGB ...
Kazuo Kamaike, Mutsumi Sano, Daisuke Sakata, Yu Nishihara, Hiroaki Amino, Akihiro Ohtsuki, Yui Okada, Takafumi Miyakawa, Makoto Kogawara, Mai Tsutsumi, Misato Takahashi, Etsuko Kawashima, Koichiro Ota, Hiroaki Miyaoka   +13 more
doaj   +1 more source

Design strategy of antidote sequence for bivalent aptamer: Rapid neutralization of high‐anticoagulant thrombin‐binding bivalent DNA aptamer‐linked M08 with HD22

Research and Practice in Thrombosis and Haemostasis, 2021
Background Bivalent thrombin‐binding aptamers (TBAs) have great potential for the treatment of thrombosis because they exhibit high anticoagulant activity, and their complementary single‐stranded DNA (ssDNA) sequences work as an antidote.
Toru Yoshitomi, Koji Wakui, Masato Miyakawa, Keitaro Yoshimoto   +3 more
doaj   +1 more source

Complementary recognition in condensed DNA: Accelerated DNA renaturation [PDF]

Journal of Molecular Biology, 1991
The functional consequences of DNA condensation are investigated. The recognition of complementary strands is profoundly modified by this critical phenomenon. (1) Condensation of denatured DNA greatly accelerates the kinetics of DNA renaturation. We propose a unifying explanation for the effects of several accelerating solvents studied here including ...
J L, Sikorav, G M, Church
openaire   +2 more sources

Base Orientation of Second DNA in RecA·DNA Filaments. Analysis by combination of linear dichroism and small angle neutron scattering in flow-oriented solution [PDF]

, 1998
To gain insight into the mechanism of pairing two complementary DNA strands by the RecA protein, we have determined the nucleobase orientation of the first and the second bound DNA strands in the RecA·DNA filament by combined measurements of linear ...
Ellouze, Christine, Kim, Hye-Kyung, Mortensen, Kell, Nordén, Bengt, Takahashi, Masayuki, Wittung-Stafshede, Pernilla   +5 more
core   +1 more source

Rapid, highly sensitive and highly specific gene detection by combining enzymatic amplification and DNA chip detection simultaneously

Sensing and Bio-Sensing Research, 2016
We have developed a novel gene detection method based on the loop-mediated isothermal amplification (LAMP) reaction and the DNA dissociation reaction on the same DNA chip surface to achieve a lower detection limit, broader dynamic range and faster ...
Koji Hashimoto, Naoko Nakamura, Keiko Ito   +2 more
doaj   +1 more source

Self-assembled endogenous DNA nanoparticles for auto-release and expression of the eGFP gene in Bacillus subtilis

Communications Biology, 2022
The DNA origami design algorithm DAEDALUS is modified to design a nanoscale cube with a two-step assembly protocol, assembling 9 modules from three DNA scaffolds and the complementary staples, combined to form the DNA origami cube.
Linfeng Cao, Ziwen Meng, Junjie Tan, Ming Ying, Meiying Bi, Yanjun Liu, Xinrui Tong, Jiaxun Wei, Lei Huang   +8 more
doaj   +1 more source

Molecular Spiders in One Dimension [PDF]

, 2007
Molecular spiders are synthetic bio-molecular systems which have "legs" made of short single-stranded segments of DNA. Spiders move on a surface covered with single-stranded DNA segments complementary to legs.
Alberts B, Alexander S, Antal T Krapivsky P L, Antal T Krapivsky P L Mallick K, Chen N Y, Derrida B, Derrida B, Derrida B, Derrida B, Fedders P A, Howard J, Kirone Mallick, Kolomeisky A B, Liggett T M, Mobilia M Reichenbach T Hinsch H Franosch T Frey E, Olah M J Stefanovic D, P L Krapivsky, Schütz G M, Shaw L B, Spohn H, Tibor Antal, Van Kampen N G   +21 more
core   +5 more sources