Results 251 to 260 of about 3,376,191 (316)

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Sequence-Specific Installation of Aryl Groups in RNA via DNA-Catalyst Conjugates. [PDF]

Angew Chem Int Ed Engl
Pratihar S, Zhong W, Feng S, Chatterjee S, Kool ET.   +4 more
europepmc   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Triplex DNA clamp regulates Cas12a activation for ssDNA and RNA sensing. [PDF]

Nucleic Acids Res
Di Pede AC, Bagheri N, Belforte E, Palone A, Rossetti M, Porchetta A.   +5 more
europepmc   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Application of SNV Detection Methods for Market Control of Food Products from New Genomic Techniques. [PDF]

Int J Mol Sci
Bernacka KU, Michalski K, Wojciechowski M, Sowa S.   +3 more
europepmc   +1 more source

Discovering, Integrating, and Reinterpreting the Molecular Logic of Life: From Classical Theories of Heredity to an Extended Functional Perspective on the Central Dogma. [PDF]

Life (Basel)
Grădinaru AC.
europepmc   +1 more source

Engineering versatile supramolecular structures with tetravalent DNA-traptavidin building blocks. [PDF]

Nanoscale Adv
Lee DG, Kim YY, Yang H, Song YK.
europepmc   +1 more source

Single-Molecule DNA Tweezers Enable Programmable Control of Enzyme Activity via Arbitrary Molecular Cues. [PDF]

Angew Chem Int Ed Engl
Godhulayyagari S, Nixon SR, Samanta D.
europepmc   +1 more source

Cooperative effects in DNA-functionalized polymeric nanoparticles.

Nanoscale
Gaki P, Klymchenko AS.
europepmc   +1 more source