Results 21 to 30 of about 3,376,191 (316)
HLA genotyping by next-generation sequencing of complementary DNA
BMC Genomics, 2017 Background Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region.
Hidenobu Segawa +2 more
doaj +1 more source
A highly sensitive electrochemical genosensor based on Co-porphyrin-labelled DNA [PDF]
, 2014 We report the use of Co-porphyrins as electrochemical tags for a highly sensitive and selective genosensor. An avian influenza virus-based DNA sequence characteristic of H5N1 was detected at femtomolar levels from competing non-complementary sequences ...
Grabowska, Iwona +8 more
core +1 more source
Molecular Therapy: Nucleic Acids, 2013 A high mutation rate leading to tumor cell heterogeneity is a driver of malignancy in human cancers. Paradoxically, however, genomic instability can also render tumors vulnerable to therapeutic attack. Thus, targeting DNA repair may induce an intolerable
Mateusz Rytelewski +5 more
doaj +1 more source
Scientific Reports, 2023 The tetrameric tumor suppressor p53 represents a great challenge for 3D-structural analysis due to its high degree of intrinsic disorder (ca. 40%). We aim to shed light on the structural and functional roles of p53’s C-terminal region in full-length ...
Alessio Di Ianni +8 more
doaj +1 more source
Cloning of human thyroglobulin complementary DNA [PDF]
FEBS Letters, 1982 Journal Article ; Research Support, Non-U.S.
Brocas, Huguette +3 more
openaire +2 more sources
Linker-mediated self-assembly of mobile DNA-coated colloids
, 2020 Developing construction methods of materials tailored for given applications with absolute control over building block placement poses an immense challenge.
Ciamarra, Massimo Pica +3 more
core +1 more source
Complexation of norfloxacin with DNA in the presence of caffeine [PDF]
, 2006 1H NMR spectroscopy (500 MHz) has been used to quantify the complexation of the antibacterial antibiotic Norfloxacin (NOR) with DNA in the presence of Caffeine (CAF). Separate studies have been made for the self-association of NOR, its hetero-association
Davies, David B. +2 more
core +1 more source
Efficiency of peptide nucleic acid-directed PCR clamping and its application in the investigation of natural diets of the Japanese eel leptocephali. [PDF]
PLoS ONE, 2011 Polymerase chain reaction (PCR)-clamping using blocking primer and DNA-analogs, such as peptide nucleotide acid (PNA), may be used to selectively amplify target DNA for molecular diet analysis.
Takeshi Terahara +7 more
doaj +1 more source
Molecular Spiders with Memory [PDF]
, 2007 Synthetic bio-molecular spiders with "legs" made of single-stranded segments of DNA can move on a surface which is also covered by single-stranded segments of DNA complementary to the leg DNA.
G. H. Weiss +8 more
core +1 more source
F1000Research, 2014 Conventionally, in a polymerase chain reaction (PCR), oligonucleotide primers bind to the template DNA in an antiparallel complementary way and the template DNA is amplified as it is.
Vikash Bhardwaj, Kulbhushan Sharma
doaj +1 more source