Results 41 to 50 of about 797,307 (281)

Fabrication of porcine DNA biosensor based on ruthenium bipyridine complex [PDF]

open access: yes, 2016
Electrochemical DNA biosensor for detection of porcine oligonucleotides based on ruthenium (II) as label redox complex has been developed. The system of biosensor is based on the modified screen printed carbon electrode (SPE) with goldnanoparticles ...
Abd Karim, Nurul Huda   +5 more
core   +1 more source

Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA

open access: yesMolecules, 2022
The development of chemically modified oligonucleotides enabling robust, sequence-unrestricted recognition of complementary chromosomal DNA regions has been an aspirational goal for scientists for many decades.
Caroline P. Shepard   +3 more
doaj   +1 more source

Why are complementary DNA strands symmetric? [PDF]

open access: yesBioinformatics, 2002
Abstract Motivation: Over sufficiently long windows, complementary strands of DNA tend to have the same base composition. A few reports have indicated that this first-order parity rule extends at higher orders to oligonucleotide composition, at least in some organisms or taxa. However, the scientific literature falls short of providing a
Pierre-François, Baisnée   +2 more
openaire   +2 more sources

Ultraaccurate genome sequencing and haplotyping of single human cells. [PDF]

open access: yes, 2017
Accurate detection of variants and long-range haplotypes in genomes of single human cells remains very challenging. Common approaches require extensive in vitro amplification of genomes of individual cells using DNA polymerases and high-throughput short ...
Bafna, Vineet   +6 more
core   +1 more source

Colloidal Flying Carpets [PDF]

open access: yes, 2009
DNA plays a special role in polymer science not just because of the highly selective recognition of complementary single DNA strands but also because bacteria can express DNA chains that are very long yet perfectly monodisperse.
Eiser, Erika, Geerts, Nienke
core   +1 more source

Comparing reverse complementary genomic words based on their distance distributions and frequencies [PDF]

open access: yes, 2017
In this work we study reverse complementary genomic word pairs in the human DNA, by comparing both the distance distribution and the frequency of a word to those of its reverse complement.
Afreixo, Vera   +7 more
core   +4 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Preparation of fluorescent DNA probe by solid-phase organic synthesis

open access: yeseXPRESS Polymer Letters, 2009
Fluorescent DNA probe based on fluorescence resonance energy transfer (FRET) was prepared by solid-phase organic synthesis when CdTe quantum dots (QDs) were as energy donors and Au nanoparticles (AuNPs) were as energy accepters.
doaj   +1 more source

Activity modulation and allosteric control of a scaffolded DNAzyme using a dynamic DNA nanostructure. [PDF]

open access: yes, 2016
Recognition of the fundamental importance of allosteric regulation in biology dates back to not long after its discovery in the 1960s. Our ability to rationally engineer this potentially useful property into normally non-allosteric catalysts, however ...
Fan, Chunhai   +7 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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