Results 51 to 60 of about 797,307 (281)

Theory on the mechanism of DNA renaturation: Stochastic nucleation and zipping

, 2015
Renaturation of complementary single strands of DNA is one of the important processes that requires better understanding in the view of molecular biology and biological physics.
Murugan, Rajamanickam, Niranjani, Gnanapragasam   +1 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Bismuth Oxide Nanoparticles/Chitosan/Modified Electrode as Biosensor for DNA Hybridization

International Journal of Electrochemical Science, 2011
An electrochemical DNA biosensor based on nanoparticles bismuth oxide Bi2O3 for DNA immobilization and hybridization detection is presented. The nano Bi2O3/chitosan-modified gold electrode (AuE) was fabricated and oligonucleotides were immobilized onto ...
Safura Taufik, Nor Azah Yusof, Tan Wee Tee, Irmawati Ramli   +3 more
doaj   +1 more source

Structural basis for CRISPR RNA-guided DNA recognition by Cascade [PDF]

, 2011
The CRISPR (clustered regularly interspaced short palindromic repeats) immune system in prokaryotes uses small guide RNAs to neutralize invading viruses and plasmids.
A Bolotin, A Noy, AJR Heck, AL Gnatt, Albert J R Heck, AM Maxam, Ambrosius P L Snijders, Arjan Barendregt, B Wiedenheft, Blake Wiedenheft, C Hale, C Pourcel, CR Hale, D Han, DH Haft, DY Lee, Edze R Westra, Egbert J Boekema, Esther van Duijn, FJ Mojica, FJ Mojica, FV Karginov, GT Oostergetel, H Deveau, H Deveau, J Carte, J Li, J van der Oost, JB Ma, JE Garneau, Jelle B Bultema, Jennifer A Doudna, John van der Oost, K Lorenzen, K Yu, Kaihong Zhou, KS Makarova, LA Marraffini, LA Marraffini, LA Marraffini, M Thomas, M van Heel, M Zhou, Magnus Lundgren, Marieke R Beijer, Mark J Dickman, Matthijs M Jore, MJ Dickman, MR Singleton, N Tahallah, P Horvath, P Horvath, R Barrangou, R Jansen, RE Haurwitz, Reinhild Wurm, RH van den Heuvel, RK Lillestøl, Rolf Wagner, S Houwing, Sakharam P Waghmare, SC Raghavan, SJ Brouns, SP Waghmare, Stan J J Brouns, T Itoh, T Wilson-Sali, TA Baker, TH Tang, V Kunin, Y Agari, Ümit Pul   +71 more
core   +5 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Non-homologous DNA end joining in normal and cancer cells and its dependence on break structures

Genetics and Molecular Biology, 2010
DNA double-strand breaks (DSBs) are a serious threat to the cell, for if not or miss-repaired, they can lead to chromosomal aberration, mutation and cancer.
Tomasz Poplawski, Elzbieta Pastwa, Janusz Blasiak   +2 more
doaj  

Deletion mutants of bacteriophage phiX174 [PDF]

, 1972
Mutants of bacteriophage phiX174 have been isolated that are less dense than wild-type phiX particles in CsCl. When mutant viral (+) strand DNA and wild-type complementary (-) strand DNA are hybridized, the resulting duplex molecules have single-stranded
Benbow, Robert M., Sinsheimer, Robert L., Zuccarelli, Anthony J.   +2 more
core  

Sequence sensitivity of breathing dynamics in heteropolymer DNA

, 2006
We study the fluctuation dynamics of localized denaturation bubbles in heteropolymer DNA with a master equation and complementary stochastic simulation based on novel DNA stability data.
B. Alberts, D. Poland, N. G. van Kampen, Oleg Krichevsky, Ralf Metzler, S. G. Delcourt, Suman K. Banik, Tobias Ambjörnsson   +7 more
core   +1 more source

DNA Renaturation at the Water-Phenol Interface [PDF]

, 2003
We study DNA adsorption and renaturation in a water-phenol two-phase system, with or without shaking. In very dilute solutions, single-stranded DNA is adsorbed at the interface in a salt-dependent manner.
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core   +4 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source