Results 191 to 200 of about 171,193 (280)

New Insights Into Changes in the DNA Methylation Pattern of the SHOX Gene in Patients With Léri‐Weill Dyschondrosteosis

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 606-618, March 2026.
ABSTRACT SHOX gene haploinsufficiency is associated with Léri‐Weill dyschondrosteosis (LWD) or idiopathic short stature (ISS) and could be caused by the structural and point mutations in the coding region and by the deletions in SHOX gene regulatory sequences. The role of the duplications in regulatory sequences is ambivalent.
Valeriia Kopytko, Katerina Hirschfeldova, Pavlina Capkova, Roman Solc   +3 more
wiley   +1 more source

Multi-omics study of molecular and genetic bases of orthostatic hypotension. [PDF]

Clin Epigenetics
Zelenova E, Daniel V, Bruttan M, Artemieva L, Spektor E, Mamchur A, Kashtanova D, Ivanov M, Abushinova G, Matkava L, Rumyantseva A, Ivashechkin A, Grebnev P, Golubnikova L, Mitrofanov S, Akopyan A, Beloshevskaya O, Saliyeva T, Tarasova I, Strazhesko I, Yudin V, Makarov V, Keskinov A, Tkacheva O, Yudin S, Skvortsova V.   +25 more
europepmc   +1 more source

Over‐Expression of a Phycocyanin‐Interferon Fusion and Differential Cleaving Efficiency in Cyanobacteria (Synechocystis sp. PCC 6803)

Biotechnology and Bioengineering, Volume 123, Issue 3, Page 752-762, March 2026.
ABSTRACT Recombinant protein expression in heterologous biological systems is an expanding field in synthetic biology. Photosynthetic organisms have the potential to provide an efficient low‐cost platform for recombinant protein production because they require minimal growth nutrients and are less susceptible to zoonotic and other contaminants ...
Bharat Kumar Majhi, Anastasios Melis
wiley   +1 more source

Cohesin regulation of genome organization in mature granule neurons in the mouse cerebellum. [PDF]

Epigenetics Chromatin
Payán Parra OA, Zhao Z, Yamada T, Yang Y.   +3 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Genome-wide methylation analysis of circulating cell-free DNA identifies an episignature in lung cancer: validation of EMP2 as a potential biomarker. [PDF]

Clin Epigenetics
Alemany-Cosme E, Cruz-Chamorro D, Hervas D, Garcia D, Martinez-Tomas R, Briones-Gomez A, Galbis-Caravajal J, Calvo A, Juan O, Lahoz A, Cases E, Palanca-Ballester C, Sandoval J.   +12 more
europepmc   +1 more source

Characterization and Identification of Pulsatilla koreana and Pulsatilla tongkangensis Seedlings Based on Morphology, Colorimetric Data, and Molecular Markers

New Zealand Journal of Crop and Horticultural Science, Volume 54, Issue 1, March 2026.
Pulsatilla tongkangensis, an endemic species growing in the limited areas in Korea, is considered endangered species, and is growing in sympatric with P. koreana enabling natural hybridization. To characterize the true to the type of P. tongkangensis, we integrated morphological traits and molecular analyses of the nuclear ribosomal ITS (nrITS) and the
Hyun Min Kim, Sang Hoon Ma, Gianluca Burchi, Young Hee Joung   +3 more
wiley   +1 more source

Genome-wide association study of economic traits and functional characterization of MAN2A2 in the Jilin White Goose. [PDF]

Poult Sci
Song Y, Ma J, Mabrouk I, Liu Q, Hua G, Ma X, Xu J, Cao H, Wang J, Li J, Liu J, Zhang J, Zhang X, Sun Y.   +13 more
europepmc   +1 more source

Single‐cell mitochondrial lineage tracing: Opportunities and challenges

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Lineage tracing using endogenous mitochondrial DNA (mtDNA) variants holds great promise for reconstructing the lineage histories of individual cells, with broad applications in oncology, developmental biology, and regenerative medicine.
Siqi Li, Kun Wang, Xin Wang, Zheng Hu
wiley   +1 more source

Decoding genomic rearrangements for cancer driver discovery. [PDF]

Mol Cells
Seo E, Park S, Park I, Bhin J.
europepmc   +1 more source