Curcuminoids Activate TET Enzymes and Increase DNA Hydroxymethylation and Active Demethylation in Leukemia Cells. [PDF]
Malkaram SA +5 more
europepmc +1 more source
Abstract Epigenetic regulation plays a central role in coordinating peanut (Arachis hypogaea L.) fruit pegging, a unique developmental process in which fertilized ovaries transition from aerial growth to subterranean pod formation. This review synthesizes current evidence demonstrating that dynamic interactions among DNA methylation, histone ...
Yohannes Gelaye, Huaiyong Luo
wiley +1 more source
Spatial variation in the mutation rate within the plant shoot apical meristem. [PDF]
Amundson KR +7 more
europepmc +1 more source
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic +2 more
wiley +1 more source
Regulated TRESLIN-MTBP loading governs initiation zones and replication timing in human DNA replication. [PDF]
Zhu X +9 more
europepmc +1 more source
The structure and evolution of the ribosomal DNA intergenic spacer in arthropods
The tandemly repeated ribosomal DNA (rDNA) multigene family (MGF) contains the transcription unit of the 45S ribosomal RNA (rRNA) precursor alternating with an intergenic spacer (IGS) that frequently contains iterated regulatory elements. Although the rRNA coding sequences are highly conserved, the IGS displays the high rates of interspecific sequence ...
openaire +1 more source
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source
A step-by-step approach to establishing an efficient genetic transformation protocol for Chlorella vulgaris using electroporation. [PDF]
Robben DM, Amin Z, Budiman C, Kumar VS.
europepmc +1 more source
Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang +51 more
wiley +1 more source
Telomeric repeat-containing lncRNA TERRA targets non-telomeric DNA in trans via R-loops. [PDF]
Shehata SN, Mendez A, Mondal T, Vaid R.
europepmc +1 more source

