Results 231 to 240 of about 117,531 (301)
Dual-dimensional profiling of host genomic variations and HPV integration in PD-L1-stratified cervical cancer via Oxford Nanopore Technology. [PDF]
Lu R, Zhang J, Ma X, Feng Y.
europepmc +1 more source
ABSTRACT Rainbow trout (Oncorhynchus mykiss) exhibit extensive genomic diversity shaped by domestication, life history and geographic origin. To advance the development of a comprehensive pangenome reference, we present new de novo genome assemblies of two genetically and ecologically distinct lines: Whale Rock (WR; wild, landlocked, Central California)
Ali Ali +9 more
wiley +1 more source
A novel phage satellite class induces prophage excision in Mycolicibacterium aichiense. [PDF]
Qian HL +5 more
europepmc +1 more source
In patients with mCSPC treated with apalutamide plus ADT, baseline ctDNA predicted earlier progression to CRPC and worse overall survival. Exploratory genome‐wide analysis identified 12 SNPs associated with apalutamide‐related skin rash. ABSTRACT Despite promising evidence of the efficacy of the androgen deprivation therapy (ADT) plus apalutamide in ...
Masaki Shiota +8 more
wiley +1 more source
We identified a Mis4 cohesin loader mutant that is specifically defective in chromatin axis formation and homologous recombination while retaining normal sister chromatid cohesion. The mis4‐LR mutant, carrying the L1150S and R1159G amino acid substitutions, exhibited reduced interaction between Mis4 and Rec8, suggesting a meiosis‐specific role for the ...
Takeshi Sakuno +3 more
wiley +1 more source
Salivary Microvesicle Methylome and Microbiome Profiles in Periodontitis: An Exploratory Study. [PDF]
Han P +5 more
europepmc +1 more source
The Role of Long Noncoding RNAs in Modulation of Stress Granules in Cancer
ABSTRACT Stress granules are dynamic cellular structures that arise in response to stress. They play an important role in cancer cell survival by modulating multiple stress responses. Long noncoding RNAs (lncRNAs) have been identified as crucial regulators of stress granule (SG) dynamics, influencing cancer development and treatment resistance. LncRNAs
Nazlı Şevval Menemenli +1 more
wiley +1 more source
Geminivirus-derived replicons: assessment for transient GFP expression in tobacco and tomato. [PDF]
Tsakirpaloglou N +4 more
europepmc +1 more source
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu +7 more
wiley +1 more source
Genome-wide mapping of stress-responsive lncRNA, uc.104, reveals the chromatin-mediated regulation of stress and plasticity-related genes in the hippocampus of chronic restraint rats. [PDF]
Verma AK +4 more
europepmc +1 more source

