Results 21 to 30 of about 171,193 (280)

FabR regulates Salmonella biofilm formation via its direct target FabB [PDF]

open access: yes, 2016
Background: Biofilm formation is an important survival strategy of Salmonella in all environments. By mutant screening, we showed a knock-out mutant of fabR, encoding a repressor of unsaturated fatty acid biosynthesis (UFA), to have impaired biofilm ...
De Coster, David   +8 more
core   +4 more sources

Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes

open access: yesNature Communications, 2022
DNMT3A is known to methylate DNA at histone H3 lysine 36 (H3K36me3)-marked transcriptionally active regions in mouse oocytes. Here the authors show that DNMT3A is also guided by H3K36me2 to methylate broad domains in genic and intergenic loci, as well as
Seiichi Yano   +6 more
doaj   +1 more source

Quadruple context-free L-System mathematical tools as origin of biological evolution [PDF]

open access: yes, 2010
It is well known that A, T, G, C annealed together early in evolution and the long stretch of DNA was found which ultimately resulted into chromosomes of different organisms.
Arunava Goswami   +4 more
core   +2 more sources

Molecular phylogenetic identification of Artemisia l. Species from Mongolia

open access: yesProceedings of the Mongolian Academy of Sciences, 2023
The Artemisia L. genus, one of the largest genera in the Asteraceae family,   consists of many medicinally important and phylogenetically unresolved species.
Bolortuya Ulziibat   +2 more
doaj   +1 more source

DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. [PDF]

open access: yes, 2014
BackgroundIn eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors.
Bunnik, Evelien M   +6 more
core   +3 more sources

Parenting stress and DNA methylation among African Americans in the InterGEN Study [PDF]

open access: yesJournal of Clinical and Translational Science, 2017
IntroductionGeneral life stress has been associated with altered DNA methylation in individuals of African Ancestry, although the relationship between parenting stress and DNA methylation has not been described. The purpose of this study was to examine the relationship between maternal parenting stress and DNA methylation among African Ancestry mother ...
Michelle L. Wright   +6 more
openaire   +3 more sources

H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape [PDF]

open access: yesNature, 2019
Enzymes catalyzing CpG methylation in DNA, including DNMT1 and DNMT3A/B, are indispensable for mammalian tissue development and homeostasis(1–4). They are also implicated in human developmental disorders and cancers(5–8), supporting a critical role of DNA methylation during cell fate specification and maintenance.
Weinberg, Daniel N.   +24 more
openaire   +3 more sources

Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development.

open access: yesPLoS ONE, 2011
The prenatal period of germ cell development is a key time of epigenetic programming in the male, a window of development that has been shown to be influenced by maternal factors such as dietary methyl donor supply.
Kirsten M Niles   +4 more
doaj   +1 more source

Identification and Characterization of an Intergenic “Safe Haven” Region in Human Fungal Pathogen Cryptococcus gattii

open access: yesJournal of Fungi, 2022
Cryptococcus gattii is a primary fungal pathogen, which causes pulmonary and brain infections in healthy as well as immunocompromised individuals. Genetic manipulations in this pathogen are widely employed to study its biology and pathogenesis, and ...
Yeqi Li   +3 more
doaj   +1 more source

Transcriptome Analyses of Tumor-Adjacent Somatic Tissues Reveal Genes Co-Expressed with Transposable Elements [PDF]

open access: yes, 2019
Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic cells.
Alberto, Adrian   +9 more
core   +2 more sources

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