Ribosomal DNA structure (after Singer and Berg, 1991).
, 2016 Ribosomal DNA structure (after Singer and Berg, 1991).
Alexander G. Dyomin (2833709) +7 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Genome-wide DNA methylation profiles and ribosomal DNA copy number at birth
EpigeneticsRibosomal DNA copy number (rDNAcn) and DNA methylation are important modulators of the human genome, both studied in relation to overall cellular function, biological ageing, and disease development.
Kathrin Barth +5 more
doaj +1 more source
The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability [PDF]
, 2012 Bidirectionally moving DNA replication forks merge at termination sites composed of accidental or programmed DNA-protein barriers. If merging fails, then regions of unreplicated DNA can result in the breakage of DNA during mitosis, which in turn can give
Steinacher, R. +8 more
core +1 more source
Information about the nuclear ribosomal DNA (nrDNA) assembly of the six Euonymus accessions.
, 2022 Information about the nuclear ribosomal DNA (nrDNA) assembly of the six Euonymus accessions.
Tae-Jin Yang (50211) +6 more
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
The unusual Gasteromycetes Lycogalopsis solmsii belongs to the gomphoid-phalloid group
Acta Mycologica, 2013 The rare tropical Gasteromycetes Lycogalopsis solmsii has been found twice at thirty years interval in the Singapore Botanic Gardens. From the most recent find a culture could be isolated, which allowed DNA extraction and sequencing of about 2000 bp from
Vincent Demoulin +3 more
doaj +1 more source
Cell Reports, 2020 Summary: Plants respond to cold stress by inducing the expression of transcription factors that regulate downstream genes to confer tolerance to freezing.
Hasi Yu +8 more
doaj +1 more source