Results 141 to 150 of about 1,937,732 (303)

LEVEL OF CHROMOSOMAL ABERRATIONS, ACTIVE RIBOSOMAL GENES DOSE AND POLYMORPHISM OF DNA REPAIR GENES IN MINERS OF THE KEMEROVO REGION

open access: yesМедицина в Кузбассе, 2018
Objective. Study of the effects of production the environment factors on the miner genome, depending on the variants of the DNA repair genes XRCC2, XRCC3, and the individual dose active ribosomal genes clusters (AcRG). Methods.
Анна Александровна Тимофеева   +7 more
doaj  

Primer and probe locations for PCR amplification, sequencing and real-time PCR of ribosomal DNA.

open access: yes, 2013
Primer and probe locations for PCR amplification, sequencing and real-time PCR of ribosomal DNA.
Weimin Ye (20887)   +1 more
core   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

open access: yesAdvanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa   +6 more
wiley   +1 more source

Protocol for diagnosis of invasive candidiasis by amplified ribosomal DNA by semi-nest PCR in plasma samples

open access: yes, 2009
Las infecciones micóticas son propias del paciente inmunocomprometido o severamente invadido. Se ha reconocido el riesgo mayor de invasión por Candida en pacientes neutropénicos, pero actualmente hay otras poblaciones de pacientes críticos no ...
Ospina Barragán, William Pascual
core  

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu   +4 more
wiley   +1 more source

The Synthesis of Amplified Ribosomal DNA

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1974
Tocchini-Valentini, Glauco P.   +3 more
openaire   +2 more sources

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

open access: yesAdvanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi   +11 more
wiley   +1 more source

Design of a Novel Diamine Biosensor to Guide the Engineering of Escherichia coli for Cadaverine Overproduction

open access: yesAdvanced Science, EarlyView.
A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng   +13 more
wiley   +1 more source

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