Results 11 to 20 of about 10,709 (124)
Early life stress inhibits expression of ribosomal RNA in the developing hippocampus. [PDF]
PLoS ONE, 2014 Children that are exposed to abuse or neglect show abnormal hippocampal function. However, the developmental mechanisms by which early life stress (ELS) impairs normal hippocampal development have not been elucidated. Here we propose that exposure to ELS
Lan Wei, Jin Hao, Arie Kaffman
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Frontiers in Oncology, 2022 Next-generation sequencing and bioinformatics analyses have clearly revealed the roles of mitochondrial ribosomal genes in cancer development. Mitochondrial ribosomes are composed of three RNA components encoded by mitochondrial DNA and 82 specific ...
Shunchao Bao +6 more
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Memorias do Instituto Oswaldo Cruz, 2004 A ribosome association factor (AF) was isolated from the yeast Sacchharomyces cerevisiae. Partial amino acid sequence of AF was determined from its fragment of 25 kDa isolated by treating AF with 2-(2-nitrophenylsulfenyl)-3-methyl-3'-Bromoindolenine ...
Heriberto Correia +5 more
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Roles of ribosomal proteins in hematologic disorders and cancers: a review
Emergency and Critical Care Medicine, 2023 . Ribosomes are important organelles for synthesizing proteins in cells. They are composed of ribosomal RNA and more than 80 ribosomal proteins. It is well known that an essential function of ribosomal proteins is to participate in protein translation ...
Jie Wang, Feng Yan
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Memorias do Instituto Oswaldo Cruz, 2013 As the distribution of Candida species and their susceptibility to antifungal agents have changed, a new means of accurately and rapidly identifying these species is necessary for the successful early resolution of infection and the subsequent reduction ...
Constanza Giselle Taverna +6 more
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Frontiers in Genetics, 2022 Introduction: Mild cognitive impairments (MCI) accompanying aging are associated with oxidative stress. The ability of cells to respond to stress is determined by the protein synthesis level, which depends on the ribosomes number.
Natalia N. Veiko +11 more
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Spatial organization of bacterial transcription and translation [PDF]
Proc. Natl. Acad. Sci. U.S.A. 113(33), 9286 (2016), 2015 In bacteria such as $\textit{Escherichia coli}$, DNA is compacted into a nucleoid near the cell center, while ribosomes$-$molecular complexes that translate messenger RNAs (mRNAs) into proteins$-$are mainly localized at the poles. We study the impact of this spatial organization using a minimal reaction-diffusion model for the cellular transcriptional ...
arxiv +1 more source
Ribosomal DNA-connecting ribosome biogenesis and chromosome biology [PDF]
Chromosome Research, 2019 Ribosomal DNA, the topic of this special issue, has long fascinated biologists. The RNA products of the ribosomal DNA are the ribosomal RNAs that are part of the ribosome. In this special issue, we focus on the sequence, molecular organization, repair, stability, copy number, and peculiar genetics of this region of the genome.
Lev Porokhovnik +2 more
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Optimal localization patterns in bacterial protein synthesis [PDF]
Physical Review E 98(3), 032417 (2018), 2019 In $\textit{Escherichia coli}$ bacterium, the molecular compounds involved in protein synthesis, messenger RNAs (mRNAs) and ribosomes, show marked intracellular localization patterns. Yet a quantitative understanding of the physical principles which would allow one to control protein synthesis by designing, bioengineering, and optimizing these ...
arxiv +1 more source
Frontiers in Genetics, 2018 Introduction: The multi-copied genes coding for the human 18, 5.8, and 28S ribosomal RNA (rRNA) are located in five pairs of acrocentric chromosomes forming so-called rDNA.
Elena M. Malinovskaya +7 more
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