Results 61 to 70 of about 315,433 (266)
Morphological and molecular characterization of Iotonchus lotilabiatus n. sp. (Nematoda: Iotonchidae) from Lao Cai Province, Vietnam [PDF]
Journal of Nematology, 2021 Tam T. T. Vu +2 more
doaj +1 more source
CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci
BiomedicinesWhile genotoxic chemotherapeutic agents are among the most effective tools to combat cancer, they are often associated with severe adverse effects caused by indiscriminate DNA damage in non-tumor tissue as well as increased risk of secondary ...
Donald P. Cameron +8 more
doaj +1 more source
Discontinuous transcription of ribosomal DNA in human cells.
PLoS ONE, 2020 Numerous studies show that various genes in all kinds of organisms are transcribed discontinuously, i.e. in short bursts or pulses with periods of inactivity between them.
Evgeny Smirnov +6 more
doaj +1 more source
PCR primers for metazoan nuclear 18S and 28S ribosomal DNA sequences. [PDF]
PLoS ONE, 2012 BACKGROUND: Metagenetic analyses, which amplify and sequence target marker DNA regions from environmental samples, are increasingly employed to assess the biodiversity of communities of small organisms. Using this approach, our understanding of microbial
Ryuji J Machida, Nancy Knowlton
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Morphological and molecular identification of filamentous fungi isolated from cosmetic powders
Brazilian Archives of Biology and Technology, 2012 Seven fungi were isolated from 50 samples of cosmetic powders. Morphological analyses and ribosomal DNA Internal Transcribed Spacers sequencing were performed which allowed the discrimination of the isolated fungi as Aspergillus fumigatus, Penicillium sp.
Flavia Cristina Jastale Pinto +8 more
doaj +1 more source
Studies on ribosomal DNA in cetaceans (whales) [PDF]
Hereditas, 2008 ARNASON U. and WIDEGREN, B. 1984. Studies on ribosomal DNA in cetaceans (whales).—Hereditas 101:149–154. Lund, Sweden. ISSN 0018–0661. Ribosomal DNA (rDNA) of 4 mysticetes and 10 odontocetes were studied by Southern blot hybridization. The material represented all extant cetacean families except the gray whales.
U, Arnason, B, Widegren
openaire +2 more sources
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source