Results 91 to 100 of about 69,429 (309)

PlantID – DNA-based identification of multiple medicinal plants in complex mixtures [PDF]

open access: yes, 2012
Background An efficient method for the identification of medicinal plant products is now a priority as the global demand increases. This study aims to develop a DNA-based method for the identification and authentication of plant species that can be ...
Bremner, Paul   +7 more
core   +2 more sources

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Specimens at the Center: An Informatics Workflow and Toolkit for Specimen-level analysis of Public DNA database data [PDF]

open access: yes, 2016
Major public DNA databases — NCBI GenBank, the DNA DataBank of Japan (DDBJ), and the European Molecular Biology Laboratory (EMBL) — are invaluable biodiversity libraries. Systematists and other biodiversity scientists commonly mine these databases for
Brown, Bethany H.   +8 more
core   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

Comparison of Internal Transcribed Spacers and Intergenic Spacer Regions of Five Common Iranian Sheep Bursate Nematodes

open access: yesIranian Journal of Parasitology, 2014
Background: Accurate identification of sheep nematodes is a critical point in epidemiological studies and monitoring of drug resistance in flocks. However, due to a close morphological similarity between the eggs and larval stages of many of these ...
Reza Nabavi   +5 more
doaj  

Resolving environmental drivers of microbial community structure in Antarctic soils [PDF]

open access: yes, 2009
Antarctic soils are extremely cold, dry, and oligotrophic, yet harbour surprisingly high bacterial diversity. The severity of environmental conditions has constrained the development of multi-trophic communities, and species richness and distribution is ...
Barrett, John E.   +4 more
core   +2 more sources

UBE2T‐Driven p53 Degradation Rewires Glycolysis to Orchestrate Lactylation‐Mediated CAFs Activation and ECM Deposition in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study integrates multi‐omics to reveal the critical role of UBE2T in driving malignancy and stromal co‐evolution in PDAC. UBE2T potentiates glycolysis by regulating p53 degradation via a positive feedback loop, thereby promoting histone H3 lysine 18 lactylation in CAFs and stromal deposition. The UBE2T inhibitor PGG represents a potential strategy
Yong Ma   +16 more
wiley   +1 more source

A Newly Identified Phallus (Phallaceae, Basidiomycota) Species, P. hadriani, in South Korea

open access: yes한국균학회지, 2020
As part of the mushroom surveys in the unexplored areas of Korea in 2019 and 2020, a phalloid fungus was found in a saline sand beach. The specimen was mainly characterized by its reticulate pileus and violet volva with well-developed rhizomorphs.
Jong Won Jo   +9 more
doaj   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

Phylogenetic diversity of Moroccan cork oak woodlands fungi : mythe ou réalité ? [PDF]

open access: yes, 2009
La variabilité interspécifique de 87 carpophores des champignons appartenant à 15 genres et 39 espèces ont été évaluées par l'analyse du polymorphisme de longueur de fragments de restriction (RFLP) de l'espaceur interne transcrit (ITS).
Abourouh, Mohamed   +5 more
core  

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