Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Telomere-to-telomere characterization of rDNA chromosome in the myxomycete Didymium iridis. [PDF]
Khan A +5 more
europepmc +1 more source
Abstract Ecosystem retrogression drives nutrient depletion, reduced productivity, and profound reorganization of soil microbial communities. Using amplicon sequencing and genome‐resolved metagenomics, we examined how cross‐domain microbial networks and functional gene potential respond to long‐term phosphorus and nitrogen limitation along the well ...
Javier A. Ceja‐Navarro +11 more
wiley +1 more source
The KMT2F histone methyltransferase interacts with the RNA polymerase I machinery to promote ribosomal RNA transcription. [PDF]
Lone KA +3 more
europepmc +1 more source
Seagrass species diversity in Tanzania based on morphological and molecular data
Seagrass diversity along the Tanzanian coast has been documented mainly through morphology, with limited molecular reference data available for Tanzania and the wider Western Indian Ocean. This study combined morphological identification with nuclear ribosomal internal transcribed spacer (ITS) and plastid ribulose‐1,5‐bisphosphate carboxylase/oxygenase
James Leonard Lusana +1 more
wiley +1 more source
Mobile intron RNA from a bacterial predator accumulates in dead archaeal cells. [PDF]
Kizina J, Lonsing A, Harder J.
europepmc +1 more source
Gene turnover in the common ancestor of all C4 grasses
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira +6 more
wiley +1 more source
In silico mapping of non-canonical DNA structures across the human ribosomal DNA locus. [PDF]
Adala JD, Knutson BA.
europepmc +1 more source
Rethinking intensification: Biodiversity‐inclusive management sustains coconut yields
Coconut palm expansion in West Africa will shape rural livelihoods and ecosystems. Our findings show that intensive practices reduce beneficial soil fungi and increase pathogens, threatening long‐term productivity. Lower‐intensity management that retains ground vegetation can sustain or boost yields while improving soil health.
Benjamin J. Roberts +10 more
wiley +1 more source
Evidence for strong purifying selection of human <i>47S</i> ribosomal RNA genes. [PDF]
Ma X +5 more
europepmc +1 more source

