Results 61 to 70 of about 35,489 (287)

A Multiplex Gene Expression Assay for Direct Measurement of RNA Transcripts in Crude Lysates of the Nematode Caenorhabditis elegans Used as a Bioanalytical Tool

Environmental Toxicology and Chemistry, Volume 42, Issue 1, Page 130-142, January 2023., 2023
Abstract Gene expression profiling in Caenorhabditis elegans has been demonstrated to be a potential bioanalytical tool to detect the toxic potency of environmental contaminants. The RNA transcripts of genes responding to toxic exposure can be used as biomarkers for detecting these toxins. For routine application in environmental quality monitoring, an
Antoine Karengera, Cong Bao, Toine F. H. Bovee, Inez J. T. Dinkla, Albertinka J. Murk   +4 more
wiley   +1 more source

Small nuclear RNAs are encoded in the nontranscribed region of ribosomal spacer DNA. [PDF]

Proceedings of the National Academy of Sciences, 1982
The structure of in vitro synthesized mouse small nuclear RNA transcribed by RNA polymerase I (snPI RNA) was studied by T1 RNase digestion pattern analysis. The patterns of four different snPI RNA species were different from those of the U1 and U2 RNA species.
Hans-Willi Jansen, Hans-Jürg Monstein, Ronald Reichel, Bernd-Joachim Benecke, Lennart Philipson   +4 more
openaire   +3 more sources

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

Advanced Science, EarlyView.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan   +35 more
wiley   +1 more source

Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin‐expressing interneurons, and inhibitory function in the auditory cortex

Glia, Volume 71, Issue 2, Page 187-204, February 2023., 2023
Main Point Loss of oligodendrocyte ErbB receptor signaling leads to A1 hypomyelination, reduced PV expression and density of PV+ neurons and synapses, hypoconnectivity of inhibitory circuits and shift of the E/I balance towards excitation. Abstract For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination
Beatriz C. Borges, Xiangying Meng, Patrick Long, Patrick O. Kanold, Gabriel Corfas   +4 more
wiley   +1 more source

Morphological and DNA-based Classification of Cyathus sp. Isolates from Thailand (Basidiomycota, Nidulariaceae)

Journal of Pure and Applied Microbiology, 2020
Cyathus sp. isolates from three areas in Thailand (Khon Kaen University, Nam Nao National Park and Phu Ruea, Loei Province) were morphologically characterized by their peridiocarp, peridioles and basidiospores.
Waraporn Sutthisa, Niwat Sanoamuang
doaj   +1 more source

DNA driven self-assembly of micron-sized rods using DNA-grafted bacteriophage fd virions [PDF]

, 2014
We have functionalized the sides of fd bacteriophage virions with oligonucleotides to induce DNA hybridization driven self-assembly of high aspect ratio filamentous particles. Potential impacts of this new structure range from an entirely new building block in DNA origami structures, inclusion of virions in DNA nanostructures and nanomachines, to a new
arxiv   +1 more source

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielman, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

A DNP‐Supported Solid‐State NMR Approach to Study Nucleic Acids In Situ Reveals Berberine‐Stabilized Hoogsteen Structures in Mitochondria

Angewandte Chemie, EarlyView.
Mitochondria are vital for energy production and rely on intricate nucleic acid structures to regulate gene expression. Using DNP‐ssNMR (dynamic nuclear polarization solid‐state NMR), we observed G‐quadruplex formation in intact mitochondria treated with berberine.
Michaela Dzurov Krafčíková, David Beriashvili, Salima Bahri, Menno Bergmeijer, Stuart C. Howes, Andrei Gurinov, Friedrich G. Förster, Gert E. Folkers, Marc Baldus   +8 more
wiley   +2 more sources

A new disease of Erica arborea in Italy caused by Neofusicoccum luteum

Phytopathologia Mediterranea, 2015
Shoot blight was observed on Erica arborea L., in a natural growing area on Caprera Island (Italy), during 2011 and 2012. Fungal isolates obtained from 324 symptomatic shoots were identified as Neofusicoccum luteum by analysis of morphological and ...
Benedetto LINALDEDDU, Bruno SCANU, Salvatore SEDDAIU, Antonio DEIDDA, Lucia MADDAU, Antonio FRANCESCHINI   +5 more
doaj   +1 more source