Results 191 to 200 of about 55,097 (302)
Conservation of giant genome structure in Brazilian and Chilean species of the genus Alstroemeria L. (Alstroemeriaceae), despite dynamism in satellite repeats. [PDF]
PlantaNascimento J +6 more
europepmc +1 more source
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Advanced NanoBiomed Research, EarlyView.Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Metal–Phenolic Coatings Enable Universal Design of Spherical Nucleic Acids
Angewandte Chemie, EarlyView.A general and straightforward strategy for constructing spherical nucleic acids (SNAs) using metal–phenolic (MP) coatings has been developed. The resulting MP‐SNAs exhibit many of the hallmark SNA properties, including enhanced cellular uptake, and serve as versatile building blocks for the programmable assembly of a diverse library of nanoparticles ...
Chaojian Chen +5 more
wiley +2 more sources
A novel phage satellite class induces prophage excision in Mycolicibacterium aichiense. [PDF]
VirologyQian HL +5 more
europepmc +1 more source
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.A coumarin‐based dual‐emission fluorophore was designed to visualize the maturation of protein liquid droplets. Upon covalent conjugation to droplet‐forming proteins, ratiometric fluorescence imaging allowed real time monitoring of droplet maturation. This probe is applicable to the analysis of droplet formation and maturation mechanisms, as well as to
Tomoya Yamamoto +6 more
wiley +2 more sources
The Satellite DNAs of Drosophila virilis
Cold Spring Harbor Symposia on Quantitative Biology, 1974 J G, Gall, E H, Cohen, D D, Atherton
openaire +2 more sources
Angewandte Chemie, EarlyView.A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang +12 more
wiley +2 more sources
The role of satellite DNA-enriched heterochromatic variants in reproductive disorders: Insights from standardized cytogenetic analysis. [PDF]
Chromosome ResPires S +5 more
europepmc +1 more source
2‐Azaazulenium Hemicyanine Dyes for NIR‐II Multimodal Imaging and Combined Phototherapy
Angewandte Chemie, EarlyView.A strategically engineered class of 2‐azaazulenium hemicyanines is developed, featuring bright fluorescence in the second near‐infrared (NIR‐II) window and multifunctional performance. SWJT‐OCH3 shows type I/II reactive oxygen species (ROS) generation and excellent photothermal activity.
Min Peng +8 more
wiley +2 more sources