Results 41 to 50 of about 55,097 (302)

Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi. [PDF]

, 2007
BACKGROUND: Trypanosomes are parasitic protozoa that diverged early from the main eukaryotic lineage. Their genomes display several unusual characteristics and, despite completion of the trypanosome genome projects, the location of centromeric DNA has ...
Bot, Christopher, Nilsson, D,, Nilsson, Daniel, Andersson, B,, Andersson, Bjorn, Bot, C,, Obado, SO, Obado, Samson O, Kelly, JM, Kelly, John M   +9 more
core   +1 more source

Regenerative capacity of old muscle stem cells declines without significant accumulation of DNA damage.

PLoS ONE, 2013
The performance of adult stem cells is crucial for tissue homeostasis but their regenerative capacity declines with age, leading to failure of multiple organs.
Wendy Cousin, Michelle Liane Ho, Rajiv Desai, Andrea Tham, Robert Yuzen Chen, Sunny Kung, Christian Elabd, Irina M Conboy   +7 more
doaj   +1 more source

Evolutionary Dynamics of Satellite DNA Repeats across the Tettigoniidae Family: Insights from Genomic Analysis

Biomolecules
Satellite DNA repeats are repetitive DNA sequences found in eukaryotic genomes, typically consisting of short DNA motifs repeated in tandem arrays. Despite the vast body of literature on satellite DNA repeats in other taxa, investigations specifically ...
Muhammad Majid, Hashim Khan, Xuanzeng Liu, Muhammad Shaheer, Yuan Huang   +4 more
doaj   +1 more source

Comparative repeatome analysis on Triatoma infestans Andean and Non-Andean lineages, main vector of Chagas disease.

PLoS ONE, 2017
Triatoma infestans is the most important Chagas disease vector in South America. Two main evolutionary lineages, named Andean and non-Andean, have been recognized by geographical distribution, phenetic and genetic characteristics.
Sebastián Pita, Francisco Panzera, Pablo Mora, Jesús Vela, Ángeles Cuadrado, Antonio Sánchez, Teresa Palomeque, Pedro Lorite   +7 more
doaj   +1 more source

Histone modifications within the human X centromere region. [PDF]

PLoS ONE, 2009
Human centromeres are multi-megabase regions of highly ordered arrays of alpha satellite DNA that are separated from chromosome arms by unordered alpha satellite monomers and other repetitive elements.
Brankica Mravinac, Lori L Sullivan, Jason W Reeves, Christopher M Yan, Kristen S Kopf, Christine J Farr, Mary G Schueler, Beth A Sullivan   +7 more
doaj   +1 more source

Satellite DNA in insects: a review [PDF]

Heredity, 2008
The study of insect satellite DNAs (satDNAs) indicates the evolutionary conservation of certain features despite their sequence heterogeneity. Such features can include total length, monomer length, motifs, particular regions and/or secondary and tertiary structures.
T, Palomeque, P, Lorite
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Replicating satellite RNA induces sequence-specific DNA methylation and truncated transcripts in plants

, 2001
Tobacco plants were transformed with a chimeric transgene comprising sequences encoding β-glucuronidase (GUS) and the satellite RNA (satRNA) of cereal yellow dwarf luteovirus.
Finnegan, E.J., Wang, M.B., Smith, N.A., Wesley, S.V., Waterhouse, P.M.   +4 more
core   +1 more source

DNA topoisomerases participate in fragility of the oncogene RET [PDF]

, 2013
Fragile site breakage was previously shown to result in rearrangement of the RET oncogene, resembling the rearrangements found in thyroid cancer. Common fragile sites are specific regions of the genome with a high susceptibility to DNA breakage under ...
Yuh-Hwa Wang (457429), Dillon, LW, Yuh-Hwa Wang, Christine E. Lehman (457427), Laura W Dillon, Dillon Laura W., Nikiforov Yuri E., Pierce Levi C. T., Wang, YH, Laura W. Dillon (457426), Lehman, Christine E., Christine E Lehman, Lehman, CE, Pierce, Levi C. T., Nikiforov, Yuri E., Pierce, LCT, Yuri E. Nikiforov (457428), Levi C T Pierce, Rybenkov, Valentin V, Wang, Yuh-Hwa, Wang Yuh-Hwa, Levi C. T. Pierce (454414), Lehman Christine E., Yuri E Nikiforov, Dillon, Laura W., Nikiforov, YE   +25 more
core   +1 more source

DNA Environment of Centromeres and Non-Homologous Chromosomes Interactions in Mouse

Cells, 2021
Although the pericentromeric regions of chromosomes that are enriched in tandemly repeated satellite DNA represent a significant part of eukaryotic genomes, they remain understudied, which is mainly due to interdisciplinary knowledge gaps. Recent studies
Victor Spangenberg, Mikhail Losev, Ilya Volkhin, Svetlana Smirnova, Pavel Nikitin, Oxana Kolomiets   +5 more
doaj   +1 more source