Results 191 to 200 of about 578,618 (302)

Isothermal nucleic acid amplification techniques: A comprehensive overview on their principle & applications as alternative to PCR. [PDF]

Pract Lab Med
Amare Amdiyee A, Sisay Tessema T.
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Dye-based qPCR assays for the separate quantification of total bacterial, fungal, arthropod, and plant DNA. [PDF]

PLoS One
Tiedge TM, Love KR, Meiklejohn KA.
europepmc   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Machine learning-optimized long single-stranded DNA synthesis technology empowers high-precision diagnostic-therapeutic integration in living cells. [PDF]

Nucleic Acids Res
Zhang Y, Xu Y, Ding Z, Cheng Y, Gao Y, Ye J, Zhang H, Li P, Wu H.   +8 more
europepmc   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Holistic determination of ends of cfDNA molecules. [PDF]

Cell Genom
Jiang P, Ma ML, Qiao R, Shi Y, Liu J, Zhou Q, Peng W, Lam WKJ, Bai J, Choy LYL, Tsui WHA, Malki Y, Kang G, Yu SCY, Xiong D, Wong GLH, Chan LL, Wong J, Chan SL, Wong VWS, Chan KCA, Lo YMD.   +21 more
europepmc   +1 more source

Single‐stranded DNA production for scaffolded DNA origami [PDF]

Biotechnology and Bioengineering, 2017
openaire   +2 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

CRISPR-based diagnostics for infectious diseases: mechanisms, advancements and clinical transformation prospects. [PDF]

Front Cell Infect Microbiol
Pan Z, Xu L, Fan Z, Cao Y, Ren F.
europepmc   +1 more source