Results 191 to 200 of about 368,244 (218)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Development of a multifunctional nucleic acid response platform utilizing the Cas12a and Cas13a integrated targeting system. [PDF]

Nucleic Acids Res
Zhou J, Liu W, Nie X, Wang X, Hu Y, Wan C, Liao Y, Pan S.   +7 more
europepmc   +1 more source

Quantitative analysis of sequential nucleic acid elution from silica paramagnetic beads.

Analyst
Varon A, Schares J, Hsieh K, Downs B, Wang TH.   +4 more
europepmc   +1 more source

Development and Optimization of CRISPR/Cas9-Assisted Recombineering in <i>Escherichia albertii</i>. [PDF]

MicroPubl Biol
Khan SA, Miller TM, Bhatt S, Li E.
europepmc   +1 more source

Double-stranded sperm DNA fragmentation measured with neutral comet assay as a predictor of IVF outcomes: evidence from three European clinics in a multi-centred prospective study. [PDF]

Hum Reprod
Humaidan P, Povlsen BB, Drakeley AJ, Jensen MB, Gabrielsen AV, McDowell SH, Moore L, Ledgerwood CJ, Rae L, Sloan A, Lawlor M, Poots L, Bailie E, Lunt RL, Newton E, Gregoire RC, Moore TCB, Esteves SC.   +17 more
europepmc   +1 more source

Lymph node-targeted DNA engages TBK1/IFN-I-driven innate immunity to induce potent T cell responses and durable memory in mice and NHPs. [PDF]

Sci Adv
Steinbuck MP, Seenappa LM, Zhan W, Palmer E, Jung MM, Jakubowski A, Cabana-Puig X, McNeil LK, Haqq CM, Fitzgerald KA, DeMuth PC.   +10 more
europepmc   +1 more source

Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA. [PDF]

J Med Virol
Lee YM.
europepmc   +1 more source

Efficient and specific DNA-targeting using single-stranded LNA/MOE mixmers and chimeric Invader:XenoRNA probes. [PDF]

Org Biomol Chem
Everly ME, Hrdlicka PJ.
europepmc   +1 more source

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Hypermutation in single-stranded DNA

DNA Repair, 2020
Natalie Saini, Dmitry A Gordenin
exaly