Results 71 to 80 of about 6,562,675 (210)

Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates [PDF]

open access: yes, 2013
This article was made OA through RCUK block grant funds.Flap endonuclease 1 (Fen1) is a highly conserved structure-specific nuclease that catalyses a specific incision to remove 5′ flaps in double-stranded DNA substrates.
Brenlla, Alfonso   +9 more
core   +1 more source

Comparative Force-Induced Structural Transitions in Single and Double-Stranded DNA from Coarse-Grained oxDNA2 Simulations

open access: yesUMYU Scientifica Journal
The mechanical response of DNA to externally applied force plays a critical role in replication, transcription, recombination, and protein-mediated genome organization.
Saratu Abdulfatah   +2 more
doaj   +1 more source

Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity [PDF]

open access: yes, 2005
When purified under rigorous conditions, some murine anti-double-stranded-DNA (anti-dsDNA) antibodies actually bind chromatin rather than dsDNA. This suggests that they may actually be antinucleosome antibodies that only appear to bind dsDNA when they ...
Lambrianides, A   +13 more
core   +1 more source

Single-stranded DNA phages [PDF]

open access: yesNature, 1980
The Single-Stranded DNA Phages. Edited By D.T. Denhardt, D. Dressler and D.S. Ray. Pp.720. (Cold Spring Harbor Laboratory: Cold Spring Harbor, New York, 1979.) $49.
openaire   +1 more source

Library construction for ancient genomics: Single strand or double strand?

open access: yesBioTechniques, 2014
A novel method of library construction that takes advantage of a single-stranded DNA ligase has been recently described and used to generate high-resolution genomes from ancient DNA samples. While this method is effective and appears to recover a greater
E. Andrew Bennett   +5 more
doaj   +1 more source

Complexation of norfloxacin with DNA in the presence of caffeine [PDF]

open access: yes, 2006
1H NMR spectroscopy (500 MHz) has been used to quantify the complexation of the antibacterial antibiotic Norfloxacin (NOR) with DNA in the presence of Caffeine (CAF). Separate studies have been made for the self-association of NOR, its hetero-association
Davies, David B.   +2 more
core   +1 more source

Characterisation of human single-stranded DNA-binding protein 1 (hSSB1) regulation by post-translational modifications [PDF]

open access: yes, 2016
Human single-stranded DNA-binding protein 1 (hSSB1) is required for the timely repair of double-strand DNA breaks, as well as the stabilisation and restart of stalled replication forks.
Ashton, Nicholas W.
core  

Comparative analysis of the taxonomic classification criteria for a number of groups of pathogenic DNA and RNA viruses based on genomic data

open access: yesВопросы вирусологии
The basis for criteria of the taxonomic classification of DNA and RNA viruses based on data of the genomic sequencing are viewed in this review. The genomic sequences of viruses, which have genome represented by double-stranded DNA (orthopoxviruses as ...
Tatiana E. Sizikova   +2 more
doaj   +1 more source

Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors

open access: yesScientific Reports, 2017
Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability.
Iman Jeddi, Leonor Saiz
doaj   +1 more source

Cells expressing murine RAD52 splice variants favor sister chromatid repair [PDF]

open access: yes, 2006
The RAD52 gene is essential for homologous recombination in the yeast Saccharomyces cerevisiae. RAD52 is the archetype in an epistasis group of genes essential for DNA damage repair.
Freeman, TC   +5 more
core   +1 more source

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