Results 51 to 60 of about 6,562,675 (210)

Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis [PDF]

, 2009
In all organisms, the protein machinery responsible for the replication of DNA, the replisome, is faced with a directionality problem. The antiparallel nature of duplex DNA permits the leading-strand polymerase to advance in a continuous fashion, but ...
Richardson, Charles C.,, Takahashi, Masateru, Vanoijen, Antoine M., Hamdan, Samir M., Joseph J. Loparo, Loparo, Joseph J., Richardson, Charles C., Takahashi, Masateru,, Oijen, Antoine M. van, Oijen, Antoine M. van,, Loparo, Joseph J.,, Antoine M. van Oijen, Samir M. Hamdan, Masateru Takahashi, Hamdan, Samir M.,, Charles C. Richardson   +15 more
core   +3 more sources

DNA insecticides based on iap3 gene fragments of cabbage looper and gypsy moth nuclear polyhedrosis viruses show selectivity for non-target insects [PDF]

Archives of Biological Sciences, 2015
DNA insecticides are novel preparations based on short single-stranded fragments of anti-apoptotic (IAP) genes of nuclear polyhedrosis viruses. In this article we report about the harmlessness of the DNA insecticides based on single-stranded ...
Oberemok Volodymyrovych Volodymyr, Laikova Volodymyrivna Kateryna, Zaitsev Sergeevich Aleksei, Nyadar Mutah Palmah, Shumskykh Nikolaevich Maksym, Gninenko Ivanovich Yuri   +5 more
doaj   +1 more source

ATPase cycle and DNA unwinding kinetics of RecG helicase [PDF]

, 2012
The superfamily 2 bacterial helicase, RecG, is a monomeric enzyme with a role in DNA repair by reversing stalled replication forks. The helicase must act specifically and rapidly to prevent replication fork collapse. We have shown that RecG binds tightly
Webb, Martin R, Powell, Ben, Ben Powell (159692), Toseland, Christopher P., Powell Ben, Webb Martin R., Toseland Christopher P., Martin R Webb, Christopher P Toseland, Ben Powell, Christopher P. Toseland (13866), Martin R. Webb (159695)   +11 more
core   +1 more source

A single strand: A simplified approach to DNA origami

Frontiers in Chemistry, 2023
Just as a single polypeptide strand can self-fold into a complex 3D structure, a single strand of DNA can self-fold into DNA origami. Most DNA origami structures (i.e., the scaffold-staple and DNA tiling systems) utilize hundreds of short single-stranded
Micah Yang, David Bakker, Dyuti Raghu, Isaac T. S. Li   +3 more
doaj   +1 more source

Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba [PDF]

, 2010
Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly ...
Petrovic-Stojanovska, Biljana, White, Malcolm F, Jelinska, Clare, Ingledew, W John, Ingledew, William John   +4 more
core   +1 more source

RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]

, 2013
Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Jo Milner, Simon J Allison, Milner, J., Allison, Simon J., Milner, Jo   +4 more
core   +1 more source

Human single-stranded DNA binding proteins are essential for maintaining genomic stability [PDF]

, 2013
The double-stranded conformation of cellular DNA is a central aspect of DNA stabilisation and protection. The helix preserves the genetic code against chemical and enzymatic degradation, metabolic activation, and formation of secondary structures ...
Cubeddu, Liza (R16726), Derek J Richard, O’Byrne, Kenneth J., Emma Bolderson, O'Byrne, Kenneth J., Nicholas W Ashton, Richard, Derek J., Kenneth J O’Byrne, Bolderson, Emma, Liza Cubeddu, Ashton, Nicholas W., Cubeddu, Liza   +11 more
core   +2 more sources

End-repair causes methylation underestimation in cell-free DNA sequencing libraries

The Journal of Liquid Biopsy
Cell-free DNA methylation sequencing provides insight into tissue of origin and chromatin structure. In some workflows, generating libraries includes end-repair.
Tobin E. Groth, Andrew A. Mishin, Varsha Rao, Ruby Tibet, Christopher J. Troll   +4 more
doaj   +1 more source

Precision Optical Measurements of DNA Structure and Synthesis [PDF]

, 2007
The structure and synthesis of DNA is important. Traditionally,high-resolution structures are solved with X-ray crystallography, and kinetic measurements are taken with consumption of large amount of reagents.
Ziyang Ma, Ma, Ziyang
core   +1 more source

Generating single-stranded DNA circles with minimal resources

MethodsX, 2021
Single-stranded circular oligonucleotides are heavily utilized in rolling circle amplification and rolling circle transcription technologies. Although various reported methodologies are available to synthesize circular, single-stranded DNA (ssDNA), the ...
Amanda Ford, LaShawna Miller, Jordan Trant, Irosha N Nawarathne   +3 more
doaj   +1 more source