Results 31 to 40 of about 366,924 (267)
Variable termination sites of DNA polymerases encountering a DNA-protein cross-link. [PDF]
PLoS ONE, 2018 DNA-protein cross-links (DPCs) are important DNA lesions induced by endogenous crosslinking agents such as formaldehyde or acetaldehyde, as well as ionizing radiation, cancer chemotherapeutic drugs, and abortive action of some enzymes.
Anna V Yudkina +2 more
doaj +1 more source
New insights on single-stranded versus double-stranded DNA library preparation for ancient DNA
BioTechniques, 2015 An innovative single-stranded DNA (ssDNA) library preparation method has sparked great interest among ancient DNA (aDNA) researchers, especially after reports of endogenous DNA content increases >20-fold in some samples.
Nathan Wales +8 more
doaj +1 more source
Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex
Nature Communications, 2022 Here the authors probe the cleavage and gate opening of single-stranded DNA by the human topoisomerase TRR using a unique single-molecule strategy to reveal structural plasticity in response to both double-stranded DNA and the helicase BLM.
Julia A. M. Bakx +8 more
doaj +1 more source
Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology
Nanomaterials, 2015 Recent progress in the combination of nucleic acids and carbon nanotubes (CNTs) has been briefly reviewed here. Since discovering the hybridization phenomenon of DNA molecules and CNTs in 2003, a large amount of fundamental and applied research has been ...
Kazuo Umemura
doaj +1 more source
Seamless Insert-Plasmid Assembly at High Efficiency and Low Cost. [PDF]
PLoS ONE, 2016 Seamless cloning methods, such as co-transformation cloning, sequence- and ligation-independent cloning (SLIC) or the Gibson assembly, are essential tools for the precise construction of plasmids.
Roger M Benoit +5 more
doaj +1 more source
Folding of single‐stranded DNA on the histone octamer [PDF]
FEBS Letters, 1985 A complex between the single‐stranded DNA of the bacteriophage M13 and the histone octamer was analyzed by electron microscopy, low‐angle X‐ray diffraction and nuclease analysis. The morphology and the diffraction pattern of the complex strongly resemble those of the nucleosome.
Caffarelli E, Leoni L, Savino M
openaire +3 more sources
Coordinated Binding of Single-Stranded and Double-Stranded DNA by UvsX Recombinase. [PDF]
PLoS ONE, 2013 Homologous recombination is important for the error-free repair of DNA double-strand breaks and for replication fork restart. Recombinases of the RecA/Rad51 family perform the central catalytic role in this process.
Robyn L Maher, Scott W Morrical
doaj +1 more source
BMC Genomics, 2019 Background Cell-free DNA (cfDNA), present in circulating blood plasma, contains information about prenatal health, organ transplant reception, and cancer presence and progression.
Christopher J. Troll +8 more
doaj +1 more source
Towards quantitative viromics for both double-stranded and single-stranded DNA viruses [PDF]
PeerJ, 2016 Background Viruses strongly influence microbial population dynamics and ecosystem functions. However, our ability to quantitatively evaluate those viral impacts is limited to the few cultivated viruses and double-stranded DNA (dsDNA) viral genomes ...
Simon Roux +8 more
doaj +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source