Results 21 to 30 of about 366,924 (267)
Single Stranded DNA Translocases can Push Single Stranded DNA Binding Proteins along Single Stranded DNA [PDF]
Biophysical Journal, 2016 Single-stranded (ss) DNA binding proteins (SSBs) protect ssDNA intermediates during genome maintenance. These SSBs must eventually be displaced or reorganized and one potential mechanism for reorganization is pushing of the SSB along the DNA by ssDNA translocases (ATP-dependent motors).
Sokoloski, Joshua E. +3 more
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UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair
Nature Communications, 2021 R loops are formed when single-stranded RNA anneals to one strand of DNA, forming three-stranded structures containing DNA-RNA hybrids and the displaced non-template single-stranded DNA. Here the authors reveal that the DNA:RNA helicase UPF1 plays a role
Greg H. P. Ngo +2 more
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RPA shields inherited DNA lesions for post-mitotic DNA synthesis
Nature Communications, 2021 Single-stranded DNA during DNA replication and repair in S/G2 needs protection by replication protein A (RPA). Here the authors reveal that RPA also shields inherited single-stranded DNA in G1, representing replication remnants from the previous cell ...
Aleksandra Lezaja +5 more
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Electrochemical Science Advances, 2022 The α‐hemolysin nanopore has attracted much attention as a tool for the single‐molecule analysis of DNA due to its potential as an ultra‐sensitive, specific, and label‐free sensing technique. The vast majority of DNA sensing research with the α‐hemolysin
Shekemi Denuga +3 more
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Cooperativity-Dependent Folding of Single-Stranded DNA
Physical Review X, 2021 The folding of biological macromolecules is a fundamental process of which we lack a full comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also folds, at physiological salt conditions, by forming nonspecific secondary ...
X. Viader-Godoy +4 more
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Continuous Approximation for Interaction Energy Transfer of DNA through Lipid Bilayers
Discrete Dynamics in Nature and Society, 2018 In this study the interaction energies for single-stranded DNA and double-stranded DNA molecules with a lipid bilayer are investigated. The 6-12 Lennard-Jones potential and continuous approximation are used to derive analytical expressions for these ...
Mansoor H. Alshehri
doaj +1 more source
Proceedings, 2020 Single-stranded DNA binding proteins (SSBs) bind to single-stranded DNA in a sequence-independent manner to prevent formation of secondary structures and protect DNA from nuclease degradation.
Olesia Werbowy +9 more
doaj +1 more source
Nanomaterials, 2013 Separation of short single- and double-stranded DNA typically requires gel electrophoresis followed by DNA extraction, which is a time consuming process.
Po-Jung Jimmy Huang, Juewen Liu
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Single-stranded binding proteins and helicase enhance the activity of prokaryotic argonautes in vitro. [PDF]
PLoS ONE, 2018 Prokaryotic argonautes are a unique class of nucleic acid-guided endonucleases putatively involved in cellular defense against foreign genetic elements.
Eric A Hunt +2 more
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Frontiers in Microbiology, 2012 Single-stranded DNA binding proteins play an essential role in DNA replication and repair. They use oligosaccharide-binding folds, a five-stranded ß-sheet coiled into a closed barrel, to bind to single-stranded DNA thereby protecting and stabilizing
Amy eStroud +2 more
doaj +1 more source