Results 11 to 20 of about 368,244 (218)

Cooperativity-Dependent Folding of Single-Stranded DNA

open access: yesPhysical Review X, 2021
The folding of biological macromolecules is a fundamental process of which we lack a full comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also folds, at physiological salt conditions, by forming nonspecific secondary ...
X. Viader-Godoy   +4 more
doaj   +1 more source

Continuous Approximation for Interaction Energy Transfer of DNA through Lipid Bilayers

open access: yesDiscrete Dynamics in Nature and Society, 2018
In this study the interaction energies for single-stranded DNA and double-stranded DNA molecules with a lipid bilayer are investigated. The 6-12 Lennard-Jones potential and continuous approximation are used to derive analytical expressions for these ...
Mansoor H. Alshehri
doaj   +1 more source

The Characteristics of New SSB Proteins from Metagenomic Libraries and Their Use in Biotech Applications

open access: yesProceedings, 2020
Single-stranded DNA binding proteins (SSBs) bind to single-stranded DNA in a sequence-independent manner to prevent formation of secondary structures and protect DNA from nuclease degradation.
Olesia Werbowy   +9 more
doaj   +1 more source

Separation of Short Single- and Double-Stranded DNA Based on Their Adsorption Kinetics Difference on Graphene Oxide

open access: yesNanomaterials, 2013
Separation of short single- and double-stranded DNA typically requires gel electrophoresis followed by DNA extraction, which is a time consuming process.
Po-Jung Jimmy Huang, Juewen Liu
doaj   +1 more source

Variable termination sites of DNA polymerases encountering a DNA-protein cross-link. [PDF]

open access: yesPLoS ONE, 2018
DNA-protein cross-links (DPCs) are important DNA lesions induced by endogenous crosslinking agents such as formaldehyde or acetaldehyde, as well as ionizing radiation, cancer chemotherapeutic drugs, and abortive action of some enzymes.
Anna V Yudkina   +2 more
doaj   +1 more source

Genetic and biochemical identification of a novel single-stranded DNA binding complex in Haloferax volcanii

open access: yesFrontiers in Microbiology, 2012
Single-stranded DNA binding proteins play an essential role in DNA replication and repair. They use oligosaccharide-binding folds, a five-stranded ß-sheet coiled into a closed barrel, to bind to single-stranded DNA thereby protecting and stabilizing
Amy eStroud   +2 more
doaj   +1 more source

Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex

open access: yesNature Communications, 2022
Here the authors probe the cleavage and gate opening of single-stranded DNA by the human topoisomerase TRR using a unique single-molecule strategy to reveal structural plasticity in response to both double-stranded DNA and the helicase BLM.
Julia A. M. Bakx   +8 more
doaj   +1 more source

New insights on single-stranded versus double-stranded DNA library preparation for ancient DNA

open access: yesBioTechniques, 2015
An innovative single-stranded DNA (ssDNA) library preparation method has sparked great interest among ancient DNA (aDNA) researchers, especially after reports of endogenous DNA content increases >20-fold in some samples.
Nathan Wales   +8 more
doaj   +1 more source

Single-stranded binding proteins and helicase enhance the activity of prokaryotic argonautes in vitro. [PDF]

open access: yesPLoS ONE, 2018
Prokaryotic argonautes are a unique class of nucleic acid-guided endonucleases putatively involved in cellular defense against foreign genetic elements.
Eric A Hunt   +2 more
doaj   +1 more source

Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology

open access: yesNanomaterials, 2015
Recent progress in the combination of nucleic acids and carbon nanotubes (CNTs) has been briefly reviewed here. Since discovering the hybridization phenomenon of DNA molecules and CNTs in 2003, a large amount of fundamental and applied research has been ...
Kazuo Umemura
doaj   +1 more source

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