Results 11 to 20 of about 368,244 (218)
Cooperativity-Dependent Folding of Single-Stranded DNA
The folding of biological macromolecules is a fundamental process of which we lack a full comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also folds, at physiological salt conditions, by forming nonspecific secondary ...
X. Viader-Godoy +4 more
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Continuous Approximation for Interaction Energy Transfer of DNA through Lipid Bilayers
In this study the interaction energies for single-stranded DNA and double-stranded DNA molecules with a lipid bilayer are investigated. The 6-12 Lennard-Jones potential and continuous approximation are used to derive analytical expressions for these ...
Mansoor H. Alshehri
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Single-stranded DNA binding proteins (SSBs) bind to single-stranded DNA in a sequence-independent manner to prevent formation of secondary structures and protect DNA from nuclease degradation.
Olesia Werbowy +9 more
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Separation of short single- and double-stranded DNA typically requires gel electrophoresis followed by DNA extraction, which is a time consuming process.
Po-Jung Jimmy Huang, Juewen Liu
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Variable termination sites of DNA polymerases encountering a DNA-protein cross-link. [PDF]
DNA-protein cross-links (DPCs) are important DNA lesions induced by endogenous crosslinking agents such as formaldehyde or acetaldehyde, as well as ionizing radiation, cancer chemotherapeutic drugs, and abortive action of some enzymes.
Anna V Yudkina +2 more
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Single-stranded DNA binding proteins play an essential role in DNA replication and repair. They use oligosaccharide-binding folds, a five-stranded ß-sheet coiled into a closed barrel, to bind to single-stranded DNA thereby protecting and stabilizing
Amy eStroud +2 more
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Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex
Here the authors probe the cleavage and gate opening of single-stranded DNA by the human topoisomerase TRR using a unique single-molecule strategy to reveal structural plasticity in response to both double-stranded DNA and the helicase BLM.
Julia A. M. Bakx +8 more
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New insights on single-stranded versus double-stranded DNA library preparation for ancient DNA
An innovative single-stranded DNA (ssDNA) library preparation method has sparked great interest among ancient DNA (aDNA) researchers, especially after reports of endogenous DNA content increases >20-fold in some samples.
Nathan Wales +8 more
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Single-stranded binding proteins and helicase enhance the activity of prokaryotic argonautes in vitro. [PDF]
Prokaryotic argonautes are a unique class of nucleic acid-guided endonucleases putatively involved in cellular defense against foreign genetic elements.
Eric A Hunt +2 more
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Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology
Recent progress in the combination of nucleic acids and carbon nanotubes (CNTs) has been briefly reviewed here. Since discovering the hybridization phenomenon of DNA molecules and CNTs in 2003, a large amount of fundamental and applied research has been ...
Kazuo Umemura
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