HIV-1 gene expression: lessons from provirus and non-integrated DNA
Retrovirology, 2004 Replication of HIV-1 involves a series of obligatory steps such as reverse transcription of the viral RNA genome into double-stranded DNA, and subsequent integration of the DNA into the human chromatin.
Wu Yuntao
doaj +1 more source
A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. [PDF]
, 2018 Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species induce IFN via separate pathways, the mechanisms by which these pathways are differentially ...
Aliyari, Saba Roghiyh +9 more
core
Search for virus specific DNA sequences and viral particles in mitochondria of avian leukemic myeloblasts [PDF]
, 1977 The intracellular localization of the avian myeloblastosis virus (AMV) genome was studied. Nuclear and mitochondrial DNAs from myeloblasts were examined by hybridization with 32P labeled AMV-RNA of high molecular weight for the presence of virus specific
Oda, Takuzo, Ogura, Hajime
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Modifies the Host Epigenome [PDF]
, 2016 The apparent simplicity of viruses hides the complexity of their interactions with their hosts. Viruses are masters at circumventing host defenses and manipulating the cellular environment for their own benefit.
Castillo-Garriga, Araceli
core
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Evidence for a newly discovered triallelic pattern in the human STR D1S1656 locus
Biotechnology & Biotechnological EquipmentIn this study, we report a case of a previously undetected triallelic pattern in the arrangement of structures at the D1S1656 locus in the Bulgarian population.
Vera Djeliova +5 more
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Human Cytomegalovirus UL34 Early and late Proteins Are Essential for Viral Replication
Viruses, 2014 UL34 is one of the ~50 genes of human cytomegalovirus (HCMV) required for replication in cell culture in human fibroblasts. UL34 encodes highly related early (UL34a) and late (UL34b) proteins that are virtually identical, with the early protein ...
Rico Rana, Bonita J. Biegalke
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Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus. [PDF]
PLoS ONE, 2010 Xenotropic murine leukemia virus (MLV)-related virus (XMRV) is a new human retrovirus associated with prostate cancer and chronic fatigue syndrome. The causal relationship of XMRV infection to human disease and the mechanism of pathogenicity have not ...
Sanggu Kim +5 more
doaj +1 more source
Kinetics of acute hepatitis B virus infection in humans [PDF]
, 2001 Using patient data from a unique single source outbreak of hepatitis B virus (HBV) infection, we have characterized the kinetics of acute HBV infection by monitoring viral turnover in the serum during the late incubation and clinical phases of the ...
Brown, D. +6 more
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