Results 41 to 50 of about 3,781,819 (347)

Human DNA decays faster with time than viral dsDNA: an analysis on HPV16 using pathology archive samples spanning 85 years

open access: yesVirology Journal, 2021
Background Quality of the nucleic acids extracted from Formalin Fixed Paraffin Embedded (FFPE) samples largely depends on pre-analytic, fixation and storage conditions.
Sara Nicolás-Párraga   +8 more
doaj   +1 more source

A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems

open access: yesNucleic Acids Research, 2011
The use of nucleases as toxins for defense, offense or addiction of selfish elements is widely encountered across all life forms. Using sensitive sequence profile analysis methods, we characterize a novel superfamily (the SUKH superfamily) that unites a ...
Dapeng Zhang, L. Iyer, L. Aravind
semanticscholar   +1 more source

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

open access: yes, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael   +9 more
core   +1 more source

Chinese Giant Salamander Iridovirus 025L Is a Viral Essential Gene

open access: yesViruses, 2023
Ranavirus is a large nucleocytoplasmic DNA virus. Chinese giant salamander iridovirus (CGSIV) belongs to the ranavirus genus, and its replication involves a series of essential viral genes.
Zijing Liu   +7 more
doaj   +1 more source

A review of DNA viral infections in psittacine birds.

open access: yesJournal of Veterinary Medical Science, 2010
To date, several DNA viral infections have been reported in psittacine birds. Psittacine beak and feather disease (PBFD) is characterized by symmetric feather dystrophy and loss and development of beak deformities.
H. Katoh, H. Ogawa, K. Ohya, H. Fukushi
semanticscholar   +1 more source

Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor. [PDF]

open access: yes, 2018
ATP-powered viral packaging motors are among the most powerful biomotors known. Motor subunits arranged in a ring repeatedly grip and translocate the DNA to package viral genomes into capsids.
Alam, Istiaq   +4 more
core   +3 more sources

Metagenomic Analysis of Respiratory Tract DNA Viral Communities in Cystic Fibrosis and Non-Cystic Fibrosis Individuals

open access: yesPLoS ONE, 2009
The human respiratory tract is constantly exposed to a wide variety of viruses, microbes and inorganic particulates from environmental air, water and food.
D. Willner   +9 more
semanticscholar   +1 more source

Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome

open access: yesNature Microbiology, 2021
Bacteriophages have important roles in the ecology of the human gut microbiome but are under-represented in reference databases. To address this problem, we assembled the Metagenomic Gut Virus catalogue that comprises 189,680 viral genomes from 11,810 ...
Stephen Nayfach   +10 more
semanticscholar   +1 more source

Biochemical prevention and treatment of viral infections – A new paradigm in medicine for infectious diseases [PDF]

open access: yes, 2004
For two centuries, vaccination has been the dominating approach to develop prophylaxis against viral infections through immunological prevention. However, vaccines are not always possible to make, are ineffective for many viral infections, and also carry
Fang, Fang, Le Calvez, Hervé, Yu, Mang
core   +3 more sources

Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA. [PDF]

open access: yesPLoS Pathogens, 2013
Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins ...
Nozomi Sakakibara   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy