Results 41 to 50 of about 751,138 (168)
Clinical Case Reports, 2021 We recently identified and treated a rare case of oral focal epithelial hyperplasia (FEH) in an adult patient with chronic graft‐vs‐host disease. This is the first report linking KTP laser therapy to successful long‐term treatment HPV32 FEH.
Joe Truong Nguyen +6 more
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DNA-PKcs is required for cGAS/STING-dependent viral DNA sensing in human cells
iScienceSummary: To mount an efficient interferon response to virus infection, intracellular pattern recognition receptors (PRRs) sense viral nucleic acids and activate anti-viral gene transcription.
Dayana B. Hristova +6 more
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Viral Genomic DNA Packaging Machinery
Tailed double-stranded DNA bacteriophage employs a protein terminase motor to package their genome into a preformed protein shell-a system shared with eukaryotic dsDNA viruses such as herpesviruses. DNA packaging motor proteins represent excellent targets for antiviral therapy, with Letermovir, which binds Cytomegalovirus terminase, already licensed as
Hawkins, Dorothy E D P +2 more
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Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections
Immunity & Ageing, 2019 Background T cells play a key role in controlling viral infections; however, the underlying mechanisms regulating their functions during human viral infections remain incompletely understood.
Yingjie Ji +15 more
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HIV-1 gene expression: lessons from provirus and non-integrated DNA
Retrovirology, 2004 Replication of HIV-1 involves a series of obligatory steps such as reverse transcription of the viral RNA genome into double-stranded DNA, and subsequent integration of the DNA into the human chromatin.
Wu Yuntao
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Viral replication organelles: the highly complex and programmed replication machinery
Frontiers in MicrobiologyViral infections usually induce the rearrangement of cellular cytoskeletal proteins and organelle membrane structures, thus creating independent compartments [termed replication organelles (ROs)] to facilitate viral genome replication.
Hao Deng +7 more
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Human Cytomegalovirus UL34 Early and late Proteins Are Essential for Viral Replication
Viruses, 2014 UL34 is one of the ~50 genes of human cytomegalovirus (HCMV) required for replication in cell culture in human fibroblasts. UL34 encodes highly related early (UL34a) and late (UL34b) proteins that are virtually identical, with the early protein ...
Rico Rana, Bonita J. Biegalke
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Fidelity of target site duplication and sequence preference during integration of xenotropic murine leukemia virus-related virus. [PDF]
PLoS ONE, 2010 Xenotropic murine leukemia virus (MLV)-related virus (XMRV) is a new human retrovirus associated with prostate cancer and chronic fatigue syndrome. The causal relationship of XMRV infection to human disease and the mechanism of pathogenicity have not ...
Sanggu Kim +5 more
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Evidence for a newly discovered triallelic pattern in the human STR D1S1656 locus
Biotechnology & Biotechnological EquipmentIn this study, we report a case of a previously undetected triallelic pattern in the arrangement of structures at the D1S1656 locus in the Bulgarian population.
Vera Djeliova +5 more
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Packaging of viral RNAs in virions of adenoviruses
Virology Journal, 2009 Earlier, we detected viral RNAs packaged in the porcine adenovirus (PAdV) -3 virions. Using Southern blot analysis, we further demonstrated that the viral RNAs were predominantly packaged in CsCl purified mature capsids (containing viral genome) than ...
Xing Li, Tikoo Suresh K
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