Results 61 to 70 of about 751,138 (168)

Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification

mBio, 2018
High-risk human papillomaviruses (HPVs) activate the ataxia telangiectasia mutated-dependent (ATM) DNA damage response as well as the ataxia telangiectasia mutated-dependent DNA-related (ATR) pathway in the absence of external DNA damaging agents for ...
Kavi Mehta, Laimonis Laimins
doaj   +1 more source

Global diversity and biogeography of DNA viral communities in activated sludge systems. [PDF]

Microbiome, 2023
Fan X, Ji M, Mu D, Zeng X, Tian Z, Sun K, Gao R, Liu Y, He X, Wu L, Li Q.   +10 more
europepmc   +1 more source

Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex.

PLoS Pathogens, 2017
Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in human bone marrow and fetal liver.
Safder S Ganaie, Wei Zou, Peng Xu, Xuefeng Deng, Steve Kleiboeker, Jianming Qiu   +5 more
doaj   +1 more source

Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells

eLife, 2016
We report that a major subpopulation of monocyte-derived macrophages (MDMs) contains high levels of dUTP, which is incorporated into HIV-1 DNA during reverse transcription (U/A pairs), resulting in pre-integration restriction and post-integration ...
Erik C Hansen, Monica Ransom, Jay R Hesselberth, Nina N Hosmane, Adam A Capoferri, Katherine M Bruner, Ross A Pollack, Hao Zhang, Michael Bradley Drummond, Janet M Siliciano, Robert Siliciano, James T Stivers   +11 more
doaj   +1 more source

CXCL10 Chemokine: A Critical Player in RNA and DNA Viral Infections. [PDF]

Viruses, 2022
Elemam NM, Talaat IM, Maghazachi AA.
europepmc   +1 more source

Metavirome Profiling and Dynamics of the DNA Viral Community in Seawater in Chuuk State, Federated States of Micronesia. [PDF]

Viruses, 2023
Jung SW, Kim KE, Kim HJ, Lee TK.
europepmc   +1 more source

Metagenomic Assessment of DNA Viral Diversity in Freshwater Sponges, Baikalospongia bacillifera. [PDF]

Microorganisms, 2022
Butina TV, Petrushin IS, Khanaev IV, Bukin YS.   +3 more
europepmc   +1 more source

HPV oncogenes expressed from only one of multiple integrated HPV DNA copies drive clonal cell expansion in cervical cancer

mBio
The integration of HPV DNA into human chromosomes plays a pivotal role in the onset of papillomavirus-related cancers. HPV DNA integration often occurs by linearizing the viral DNA in the E1/E2 region, resulting in the loss of a critical viral early ...
Lulu Yu, Vladimir Majerciak, Alexei Lobanov, Sameer Mirza, Vimla Band, Haibin Liu, Maggie Cam, Stephen H. Hughes, Douglas R. Lowy, Zhi-Ming Zheng   +9 more
doaj   +1 more source

Longitudinal Monitoring of DNA Viral Loads in Transplant Patients Using Quantitative Metagenomic Next-Generation Sequencing. [PDF]

Pathogens, 2022
Carbo EC, Russcher A, Kraakman MEM, de Brouwer CS, Sidorov IA, Feltkamp MCW, Kroes ACM, Claas ECJ, de Vries JJC.   +8 more
europepmc   +1 more source

The Intricate Interplay between APOBEC3 Proteins and DNA Tumour Viruses

Pathogens
APOBEC3 proteins are cytidine deaminases that play a crucial role in the innate immune response against viruses, including DNA viruses. Their main mechanism for restricting viral replication is the deamination of cytosine to uracil in viral DNA during ...
Nika Lovšin, Bhavani Gangupam, Martina Bergant Marušič   +2 more
doaj   +1 more source