Results 111 to 120 of about 3,131 (155)

糖尿病性骨质疏松与脂肪干细胞成骨分化能力损害机制研究进展

Zhongshan Daxue xuebao. Yixue kexue ban
糖尿病（DM）患者长期高血糖所致骨质疏松及骨愈合延迟等骨骼并发症已成为显著降低其生活质量的临床难题，其核心机制与脂肪干细胞（ADSCs）成骨分化能力受损密切相关。在骨组织工程中，ADSCs因取材微创、增殖迅速及多向分化能力被视为骨缺损修复的种子细胞，但DM病理环境显著抑制了ADSCs的成骨潜能，进而影响了糖尿病骨病的治疗效率。因此，探索高糖环境下ADSCs成骨能力障碍的深层机制对优化糖尿病骨病的治疗策略具有重要意义。本文系统回顾并总结了高糖环境中ADSCs迁移能力下降、增殖活性降低 ...
韩芳, 田峻
doaj  

[Research progress on ionic liquid-functionalized magnetic Fe₃O₄ nanomaterials in sample pretreatment- chromatographic analysis]. [PDF]

Se Pu
Li JX, Zhao LZ, Sun XM, He ZQ, Cao HL, Luo YJ, Yang B.   +6 more
europepmc   +1 more source

[PINK1 suppresses colorectal cancer cell growth through epigenetic regulation of histone modifications]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Wang M, Luan S, Fan X, Han D, Zhu Y.
europepmc   +1 more source

[Shihu Mixture alleviates diabetic cardiomyopathy in rats by Sirt3-mediated upregulation of myocardial mitochondrial mitophagy pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Lin X, He Y, Shi H, Liu J, Hu H.
europepmc   +1 more source

水凝胶微珠在早期无创诊断结直肠癌的研究进展

Zhongguo shiyan zhenduanxue
结直肠癌（Colorectal cancer，CRC）是全球高发病率和高死亡率的恶性肿瘤之一，早期诊断对改善患者预后至关重要。然而，传统诊断方法如结肠镜检查和粪便潜血试验（Fecal occult blood test，FOBT）存在侵入性、灵敏度不足等局限性。水凝胶微珠技术因其优异的生物相容性、高负载能力和可调控的物理化学性质，在 CRC早期无创诊断中展现出巨大潜力。本文综述了水凝胶微珠的技术原理、制备方法（如微流体技术、乳化法、电喷雾、光刻法和 3D打印）及其在 CRC核酸标志物（如基因突变、甲基化
王少妍, 秦宇, 付渤钧, 张海山
doaj  

[Quantitative analysis of DNA methylation by pyrosequencing and MassARRAY technique for age estimation: a comparative study]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2020
Wang L, Peng F, Zhao H, Li S, Sun X, Liu T, Feng L.   +6 more
europepmc   +1 more source

[Progress in metabolomics of multiple myeloma]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Ye X, Sun ZX, Qu XY, Fan L.
europepmc   +1 more source

[Expression and prognostic value of mothers against decapentaplegic homolog 7 in head and neck squamous cell carcinoma]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Zhao H, Zhong X, Huang Y, Fei W.
europepmc   +1 more source

[The role of extracellular vesicles in early embryo development and their application in assisted reproductive technologies]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Wang H, Li X, Lan H, Tong X.
europepmc   +1 more source

[Advances in application of cell imprinting technology in biomedical field]. [PDF]

Se Pu
Zhao XM, Zhang ZY, Sun WJ, Qing GY.
europepmc   +1 more source