Results 191 to 200 of about 1,958,390 (304)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

DRBP-EDP: classification of DNA-binding proteins and RNA-binding proteins using ESM-2 and dual-path neural network. [PDF]

NAR Genom Bioinform
Mu Q, Yu G, Zhou G, He Y, Zhang J.
europepmc   +1 more source

DNA-binding proteins studied by mechanical manipulation and AFM imaging of single DNA molecules. [PDF]

Biophys Rep, 2022
Zhao X, Liu XP, Yan J.
europepmc   +1 more source

DNA-Binding Protein SATB1 [PDF]

, 2020
openaire   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Inner membrane components of the plasmid pKM101 type IV secretion system TraE and TraD are DNA-binding proteins. [PDF]

Sci Rep
Jemouai Z, Sverzhinsky A, Sygusch J, Pascal J, Baron C.   +4 more
europepmc   +1 more source

The Hypersaline Archaeal Histones HpyA and HstA Are DNA Binding Proteins That Defy Categorization According to Commonly Used Functional Criteria. [PDF]

mBio, 2023
Sakrikar S, Hackley RK, Martinez-Pastor M, Darnell CL, Vreugdenhil A, Schmid AK.   +5 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Sonication-assisted protein extraction improves proteomic detection of membrane-bound and DNA-binding proteins from tumor tissues. [PDF]

Nat Protoc
Li QK, Lih TM, Clark DJ, Chen L, Schnaubelt M, Zhang H.   +5 more
europepmc   +1 more source

WHIRLIES Are Multifunctional DNA-Binding Proteins With Impact on Plant Development and Stress Resistance. [PDF]

Front Plant Sci, 2022
Krupinska K, Desel C, Frank S, Hensel G.
europepmc   +1 more source