Results 131 to 140 of about 219,109 (274)

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

Advanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang, Zhinang Yin, Yanqiong Shen, Gang Feng, Fangfang Dai, Dongyong Yang, Zhimin Deng, Jing Yang, Ruizhi Chen, Leifeng Yang, Xian Chen, Qing Sun, Chunyu Huang, Yanxiang Cheng, Hongbing Deng, Lianghui Diao, Longfei Li, Tailang Yin   +17 more
wiley   +1 more source

A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination

eLife
Small RNAs target their complementary chromatin regions for gene silencing through nascent long non-coding RNAs (lncRNAs). In the ciliated protozoan Tetrahymena, the interaction between Piwi-associated small RNAs (scnRNAs) and the nascent lncRNA ...
Salman Shehzada, Tomoko Noto, Julie Saksouk, Kazufumi Mochizuki   +3 more
doaj   +1 more source

Mode of inhibition of HIV-1 reverse transcriptase by polyacetylenetriol, a novel inhibitor of RNA- and DNA-directed DNA polymerases [PDF]

, 2002
Shoshana Loya, Amira Rudi, Yoel Kashman, Amnon Hizi   +3 more
openalex   +1 more source

Arabidopsis RNA Polymerase IV generates 21–22 nucleotide small RNAs that can participate in RNA-directed DNA methylation and may regulate genes [PDF]

, 2020
Kaushik Panda, Andrea D. McCue, R. Keith Slotkin   +2 more
openalex   +1 more source

Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells

Advanced Science, EarlyView.
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang, Jane Frederick, Karla Isabel Medina, Elizabeth Thomas Bartom, Luay Matthew Almassalha, Yaqi Zhang, Greta Wodarcyk, Hao Huang, I Chae Ye, Ruyi Gong, Cody Levi Dunton, Alex Duval, Paola Carrillo Gonzalez, Joshua Pritchard, John Carinato, Iuliia Topchu, Junzui Li, Zhe Ji, Mazhar Adli, Vadim Backman, Daniela Matei   +20 more
wiley   +1 more source

Studies of RNA chain initiation by Escherichia coli RNA polymerase bound to T7 DNA. Direct analysis of the kinetics and extent of RNA chain initiation at T7 promoter A1.

, 1979
William C. Nierman, Michael J. Chamberlin   +1 more
openalex   +1 more source

The C-terminal zinc finger of the catalytic subunit of DNA polymerase is responsible for direct interaction with the B-subunit [PDF]

, 2004
Javier Sánchez, Leonora F. Ciufo, Xiaowen Yang, Stephen Kearsey, Stuart A. MacNeill   +4 more
openalex   +1 more source

DNA-directed RNA Polymerase [PDF]

, 2020

openalex   +1 more source

Genome‐Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu, Lei Huang, Guoli Li, Biao Deng, Xiaoxiao Wang, Hu Yang, Yuanyuan Zhang, Qiuhan Wen, Chao Wang, Jingshu Zhang, Yunxiang Zhao, Kui Li, Yuwen Liu   +12 more
wiley   +1 more source

DNA-directed DNA Polymerase and Strand Displacement Activity of the Reverse Transcriptase Encoded by the R2 Retrotransposon [PDF]

, 2007
Anna Kurzyńska‐Kokorniak, Varuni K. Jamburuthugoda, Arkadiusz Bibiłło, Thomas H. Eickbush   +3 more
openalex   +1 more source