Results 151 to 160 of about 219,109 (274)

Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion

Advanced Science, EarlyView.
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen, Zongwei Li, Zhihong Fang, Zou Li, Daoyan Yang, Yuan Li, Shurong Liu, Zhiqiang Liu, Rui Liu, Huan Liu   +9 more
wiley   +1 more source

A nonsense mutation causing decreased levels of insulin receptor mRNA: detection by a simplified technique for direct sequencing of genomic DNA amplified by the polymerase chain reaction.

, 1990
Takashi Kadowaki, Hiroaki Kadowaki, Simeon I. Taylor   +2 more
openalex   +1 more source

PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair [PDF]

, 2018
Andrew Craxton, Deeksha Munnur, Rebekah Jukes-Jones, George Skalka, Claudia Langlais, Kelvin Cain, Michal Malewicz   +6 more
openalex   +1 more source

Deoxyuridine triphosphates modified with tyrosine aromatic groups for direct electrochemical detection of double-stranded DNA products of isothermal recombinase polymerase amplification

, 2021
Elena V. Suprun, Svetlana A. Khmeleva, Gulnaz R. Kutdusova, K. G. Ptitsyn, В. Е. Кузнецова, С. А. Лапа, А. В. Чудинов, Sergey P. Radko   +7 more
openalex   +1 more source

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

Advanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen, Lizhi Guan, Chao Wu, Yiwen Gong, Lei Wu, Minchun Zhang, Zhiwen Cao, Yufei Chen, Chengcan Yang, Bing Wang, Yunqi Li, Bin Li, Yufang Bi, Guang Ning, Jiqiu Wang, Weiqing Wang, Ruixin Liu   +16 more
wiley   +1 more source

Addendum: Site-directed mutagenesis using Pfu DNA polymerase and T4 DNA ligase

BioTechniques, 2005
doaj   +1 more source

Assembly of a functional replication complex without ATP hydrolysis: a direct interaction of bacteriophage T4 gp45 with T4 DNA polymerase.

, 1993
Michael K. Reddy, Steven E. Weitzel, Peter H. von Hippel   +2 more
openalex   +1 more source

Arabidopsis RNA Polymerase IV generates 21-22 nucleotide small RNAs that can participate in RNA-directed DNA methylation and may regulate genes [PDF]

, 2019
Kaushik Panda, Andrea D. McCue, R. Keith Slotkin   +2 more
openalex   +1 more source

Rapid and direct detection of male DNA by recombinase polymerase amplification assay

, 2022
Seiji Kubo, Hideki Niimi, Isao Kitajima
openalex   +2 more sources

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source