The properties of Msh2-Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair. [PDF]
, 2018 DNA mismatch repair (MMR) corrects mispaired DNA bases and small insertion/deletion loops generated by DNA replication errors. After binding a mispair, the eukaryotic mispair recognition complex Msh2-Msh6 binds ATP in both of its nucleotide-binding sites,
Graham, William J +2 more
core
Designing the Next Generation of Biomaterials through Nanoengineering
Advanced Materials, EarlyView.Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr. +3 more
wiley +1 more source
Polymerase (DNA directed), delta 2, regulatory subunit 50kDa (POLD2); cytochrome c, somatic (CYCS); metallothionein 1A (MT1A; MTC); aldo-keto reductase family 1, member C3 (AKR1C3); YME1-like 1 (YME1L1); annexin A7 (ANXA7); programmed cell death 4 (PDCD4) [PDF]
, 2009 openalex +1 more source
Bringing Attomolar Detection to the Point‐of‐Care with Nanopatterned DNA Origami Nanoantennas
Advanced Materials, EarlyView.Single DNA molecules are captured within the hotspots of DNA origami NanoAntennas arranged on a chip surface. Fluorescence is amplified, enabling direct detection on a point‐of‐care‐compatible imaging setup (visualized as bright signals against a dark background).
Renukka Yaadav +13 more
wiley +1 more source
Isolation and Characterization of RNA-Directed DNA Polymerase from a B-Type RNA Tumor Virus
Journal of Virology, 1974 A. Dion, A. Vaidya, G. Fout, D. Moore
semanticscholar +1 more source
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Advanced Materials, EarlyView.Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
Skip DNA extraction and go direct to PCR with VersaTaq™ Direct PCR Polymerase [PDF]
, 2015 openalex +1 more source
3D‐Printed Unibody Microfluidic Devices for Organ‐on‐Chip Applications
Advanced Materials Technologies, EarlyView.A practical approach is demonstrated to 3D printing unibody microfluidic Organ‐on‐Chip (OoC) devices using commercial resins and desktop DLP printers. The demonstrated functional devices support 2D monolayers, 3D spheroids, and barrier tissues. With optimised design and post‐processing techniques, leak‐free, biocompatible microchannels and membranes ...
Louis Jun Ye Ong +8 more
wiley +1 more source
A direct role of RNA polymerase III and RNA in DNA homologous recombination
, 2021 Sijie Liu, Daochun Kong
openalex +1 more source
Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic
Advanced Sensor Research, EarlyView.This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin +2 more
wiley +1 more source