Results 211 to 220 of about 235,447 (289)

DNA-Directed RNA Polymerase III Subunit RPC10 [PDF]

, 2020
openaire   +1 more source

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

Advanced Science, EarlyView.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang, Jianxin Fu, Tiandan Long, Chao Zhang, Fuhua Fan, Zhaobo Lang, Jian‐Kang Zhu   +6 more
wiley   +1 more source

How to spare gut microbiota from antibiotic effects? PK-PD based innovative strategies, target specificity, and molecule-to-medicinal properties. [PDF]

RSC Med Chem
Rai A, Newaskar V, Roy N, Guchhait SK.
europepmc   +1 more source

DNA-Directed RNA Polymerase II Subunit RPB1 [PDF]

, 2020
openaire   +1 more source

Single‐Nucleus RNA Sequencing Reveals Mid‐Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate

Advanced Science, EarlyView.
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong, Xin‐Wei Huang, Qiu‐Xia Xiao, Ying‐Gang Zheng, Hao‐Yue Qin, Chang‐Le Fang, Li Chen, Ruo‐Lan Du, Qiu‐Lin Wang, Li‐Ren Huangfu, Ye‐Qing Fei, Yang‐Yang Zhao, Chen‐Yang Zhai, Ze‐Mian Chen, Shi‐Kun Yuan, Yu‐Ji Zhou, Xing‐Man He, Ting‐Ting Zhi, Xiao‐He Tian, Ting‐Hua Wang   +19 more
wiley   +1 more source

Directed assembly of single-stranded DNA fragments for data storage via protein-free catalytic splint ligation. [PDF]

Nucleic Acids Res
Mendonsa G, Chari S, Bao M, Herdendorf B, Reddy A.   +4 more
europepmc   +1 more source

The CIC::DUX4 oncoprotein maintains DNA integrity through direct regulation of the catalytic subunit of DNA polymerase epsilon (POLE) [PDF]

Zeinab Kosibaty, Cuyler Luck, Ross A. Okimoto   +2 more
openalex   +1 more source

DNA-Directed RNA Polymerase III Subunit RPC2 [PDF]

, 2020
openaire   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Sexually Transmitted Infections: Usefulness of Molecular Methods for Microorganism Detection in Stored Sexual Assault Samples. [PDF]

Int J Mol Sci
Cainé L, Eira A, Fadoni J, Franco M, Correia Dias H, Amorim A.   +5 more
europepmc   +1 more source