Results 261 to 270 of about 235,447 (289)

High-Fidelity, One-Pot Nucleic Acid Amplification via OMEGA IsrB Nickase Cycling for Clinical Pathogen Detection. [PDF]

JACS Au
Liao Y, Sun Y, Yu H, Ren J, He F.
europepmc   +1 more source

Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo, Jiayun Liu, Yunxin Su, Tao Jiang, Xincan Wu, Peng Gao, Tao Qin, Mengyuan Wu, Qingqing Li, Shujun Zhang, Baorong He, Yongxiang Wang, Xiaodong Guo, Wei Zhou, Shujie Zhao, Jin Fan, Jian Chen, Guoyong Yin   +17 more
wiley   +1 more source

The Power of Old Hats: Rediscovering Inosine-EpPCR to Create Starting Libraries for Whole-Cell-SELEX. [PDF]

Biosensors (Basel)
Bolotnikov G, Kissmann AK, Gruber D, Bellmann A, Hasler R, Kleber C, Knoll W, Rosenau F.   +7 more
europepmc   +1 more source

TWF2 Drives Tumor Progression and Sunitinib Resistance in Renal Cell Carcinoma through Hippo Signaling Suppression

Advanced Science, EarlyView.
Twinfilin actin‐binding protein (TWF2) is upregulated in sunitinib‐resistant renal cell carcinoma (RCC) cells, where it interacts with YAP and protects YAP from degradation. Stabilized YAP translocates into the nucleus and activates transcription of target genes, promoting RCC progression and drug resistance.
Liangmin Fu, Wuyuan Liao, Youyan Tan, Hansen Lin, Kun Ye, Xinwei Zhou, Mingjie Lin, Kangbo Huang, Minyu Chen, Jietao Wei, Haoqian Feng, Yuhang Chen, Jinwei Chen, Bohong Guan, Shan Li, Zhengkun Zhang, Anze Yu, Zihao Feng, Lizhen Zhang, Guannan Shu, Jun Lu, Wei Chen, Yihui Pan, Jiefeng Yang, Junhang Luo, Li Luo   +25 more
wiley   +1 more source

Mouse PrimPol Outperforms Its Human Counterpart as a Robust DNA Primase. [PDF]

Int J Mol Sci
Carvalho G, Guerra S, Martínez-Jiménez MI, Blanco L.   +3 more
europepmc   +1 more source

Unveiling ctDNA Response: Immune Checkpoint Blockade Therapy in a Patient with POLE Mutation-Associated Early-Onset Colon Cancer. [PDF]

Curr Oncol
Ramachandran R, Cannon M, Peshin S, Kundranda M, Scott AJ.   +4 more
europepmc   +1 more source

Isothermal signal amplification-mediated nanozyme capture on DNA tetrahedra for ultrasensitive amperometric immunoassay of Epstein-Barr virus latent membrane protein 1. [PDF]

Front Chem
Liao L, Li Z, Liu Z, Qiu B, Guo W.
europepmc   +1 more source

Methionine Restriction Differentially Modulates Expression of Genes in the Base Excision Repair Pathway in Rat Brain and Liver. [PDF]

Biomolecules
Gredilla R, Lopez-Torres M, Sanchez-Roman I.   +2 more
europepmc   +1 more source

Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates. [PDF]

Commun Biol
Wang H, Meng L, Otaegi-Ugartemendia S, Condezo GN, Blanc-Mathieu R, Stokke R, Langvad MR, Brandt D, Kalinowski J, Dahle H, San Martín C, Ogata H, Sandaa RA.   +12 more
europepmc   +1 more source

Molecular Identification and Characterization of a Novel Gammaherpesvirus in Wild Rabbits. [PDF]

Viruses
Abade Dos Santos FA, Duarte A, Varandas IC, Barros SS, Henriques AM, Fagulha T, Duarte MD.   +6 more
europepmc   +1 more source