Results 261 to 270 of about 693,481 (331)

Screening strategy to identify Cas9 variants with higher HDR activity based on diphtheria toxin. [PDF]

open access: yesJ Biomed Sci
Matsumoto D   +6 more
europepmc   +1 more source

RNA-Directed DNA Methylation: The Evolution of a Complex Epigenetic Pathway in Flowering Plants.

open access: yesAnnual Review of Plant Biology, 2014
M. Matzke, T. Kanno, A. Matzke
semanticscholar   +1 more source

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

open access: yesAdvanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian   +12 more
wiley   +1 more source

DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs. [PDF]

open access: yesNucleic Acids Res
van der Sluijs RV   +19 more
europepmc   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

open access: yesAdvanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang   +13 more
wiley   +1 more source

Direct Cloning of PCR Products Amplified with Pwo DNA Polymerase

open access: gold, 1996
S. Hinnisdaels   +2 more
openalex   +1 more source

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy

open access: yesAdvanced Science, EarlyView.
MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer   +18 more
wiley   +1 more source

Mechanism for Nucleotidyl Transfer in LINE-1 ORF2p Revealed by QM/MM Simulations. [PDF]

open access: yesInt J Mol Sci
Polyakov IV   +4 more
europepmc   +1 more source

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