Precision gene editing: The power of CRISPR-Cas in modern genetics. [PDF]
Mol Ther Nucleic AcidsJoo JH, Lee S, Kim KP.
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Structure of the bacteriophage PhiKZ non-virion RNA polymerase bound to a p119L open promoter analogue. [PDF]
IUCrJChen CS +3 more
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A Simple Restriction Fragment Length Polymorphism-Based Method for Multiplex Testing of Thrombosis Risk Factors FV Leiden and <i>F2</i> G20210A with Highly Sensitive Contamination Detection. [PDF]
Int J Mol Scide Mazancourt P +4 more
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Synthesis and Incorporation of a pH-Responsive Nucleoside Into DNA Sequences. [PDF]
ChembiochemOgel E, Becker S.
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The DNA-directed RNA polymerases of soybean
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973Abstract Four cellular RNA polymerases have been partially purified from hypocotyls of soybean ( Glycine max ). Enzyme isolation from nuclear preparations indicate the DEAE polymerases I and II are localized within the nucleus. Inhibitor studies showed that DEAE polymerase II was preferentially inhibited by α-amanitin, DEAE peaks III and IV were ...
P A, Horgen, J L, Key
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A DNA-directed DNA polymerase from murine liver mitochondria
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975A DNA-directed DNA polymerase has been isolated from murine liver mitochondria. The mitochondrial DNA polymerase is distinguishable from other DNA polymerases found in the nucleus and cytosol of murine cells by several enzymatic and physical properties. It is stimulated 5--6-fold by 0.15 M KCl, does not require a sulfhydryl reducing agent for activity,
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Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor
Folia Microbiologica, 1989DNA-directed RNA polymerase was isolated from wild-type and mutant (asporogenic and granaticin overproducing) Streptomyces granaticolor. The effect of granaticin on the enzyme activity was compared with that of standard transcription inhibitors, rifampicin and rifamycin SV and shown to be zero.
J, Smardová +3 more
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The aryl hydrocarbon receptor (AhR) mediates a variety of biological responses to ubiquitous environmental pollutants. AhR is ligand activated transcription factor with high affinities for aromatic planar compounds such as β-naphthoflavone (BNF), 3-methylcholanthrene (3-MC), benzo[a]pyrene (BaP) or dioxin (TCDD).
Damian, Brauze +1 more
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Mitochondrial DNA-directed RNA polymerase from Saccharomyces cerevisae mitochondria
Biochemical and Biophysical Research Communications, 1971Abstract A DNA-directed RNA polymerase activity has been detected in yeast mitochondrial extracts which is sensitive to rifampicin. This activity is distinct from that found in the nucleus and cytoplasm, and is possibly coded for, or under the control of the mitochondrial genome.
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On the Binding of Rifampicin to the DNA‐Directed RNA Polymerase from Escherichia coli
European Journal of Biochemistry, 1973The capacity of RNA polymerase to bind the antibiotic rifampicin is rather sensitive to conditions which lead to conformational changes in the enzyme. Repeated freezing and thawing in 1 M LiCl as well as treatment with guanidinium chloride destroys the binding affinity of the enzyme for the inhibitor. Similarly rifampicin does not associate with any of
U I, Lill, G R, Hartmann
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