Results 151 to 160 of about 98,603 (254)
S. Lahmy +6 more
semanticscholar +1 more source
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou +14 more
wiley +1 more source
Deciphering the Role of DNA Polymerase Eta on the Incorporation and Bypass of Inosine and Cell Cycle Arrest. [PDF]
Lin JC, Averill JR, Jung H.
europepmc +1 more source
DNA damage regulates direct association of TOR kinase with the RNA polymerase II–transcribedHMO1gene
Arvind Panday +5 more
openalex +1 more source
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen +22 more
wiley +1 more source
Plant tolerance mechanisms to DNA-damaging UV stress. [PDF]
Asik E, Kashif SZ, Oztas O.
europepmc +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Integrative Transcriptomic and Metabolomic Analysis Provides New Insights into the Multifunctional ARGONAUTE 1 Through an <i>Arabidopsis ago1-38</i> Mutant with Pleiotropic Growth Defects. [PDF]
Chen X +5 more
europepmc +1 more source
Evidence for direct involvement of T7 RNA polymerase bacteriophage DNA replication [PDF]
David C. Hinkle
openalex +1 more source

