The linker region of a development-specific DNA polymerase X ensures efficient repair of programmed DNA double-strand breaks in Parameciumtetraurelia. [PDF]
Verron B+5 more
europepmc +1 more source
Initiation of DNA synthesis by the avian oncornavirus RNA-directed DNA polymerase: tryptophan tRNA as the major species of primer RNA [PDF]
William R. Folk, Anthony J. Faras
openalex +1 more source
Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao+11 more
wiley +1 more source
Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency. [PDF]
Zhai L+10 more
europepmc +1 more source
RNase H and RNA-directed DNA polymerase: associated enzymatic activities of murine mammary tumor virus [PDF]
Arnold S. Dion+2 more
openalex +1 more source
A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma+13 more
wiley +1 more source
High-throughput Kinetics using capillary Electrophoresis and Robotics (HiKER) platform used to study T7, T3, and Sp6 RNA polymerase misincorporation. [PDF]
Carter ZI+3 more
europepmc +1 more source
Human Leukemic Cells: RNA‐Directed DNA Polymerase [PDF]
L.S. Desai+3 more
openalex +1 more source
Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong+17 more
wiley +1 more source
Bacteriophage RNA polymerases: catalysts for mRNA vaccines and therapeutics. [PDF]
Nair A, Kis Z.
europepmc +1 more source