Results 231 to 240 of about 98,603 (254)

Genome-Wide Identification and Expression Profiling of the RNA-Directed DNA Methylation Pathway Genes in <i>Cucumis sativus</i> L. [PDF]

Plants (Basel)
Ma L, Li Z, Qiu L, Gu J, Shi P, Cao X, Zhang X, Xu X, Ma Y.   +8 more
europepmc   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Understanding off-target growth defects introduced to influenza A virus by synonymous recoding. [PDF]

RNA
Sharp CP, Thompson BH, Hoque AF, Diebold O, Tesla B, Kurian D, Simmonds P, Digard P, Gaunt E.   +8 more
europepmc   +1 more source

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

Ancient Host-Virus Gene Transfer Hints at a Diverse Pre-LECA Virosphere. [PDF]

J Mol Evol
Karki S, Barth ZK, Aylward FO.
europepmc   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Nucleic acid joining enzymes: biological functions and synthetic applications beyond DNA. [PDF]

Biochem J
Blackstock C, Walters-Freke C, Richards N, Williamson A.   +3 more
europepmc   +1 more source

Strategic Preparedness of Broad-Spectrum Antivirals for Rapid Response Towards Next Pandemics. [PDF]

Small Sci
N SR, Jin GW, Choy JH.
europepmc   +1 more source

Comparison of Commercially Available Thermostable DNA Polymerases with Reverse Transcriptase Activity in Coupled Reverse Transcription Polymerase Chain Reaction Assays. [PDF]

Methods Protoc
Smirnova EV, Blagodatskikh KA, Barsova EV, Varlamov DA, Kramarov VM, Ignatov KB.   +5 more
europepmc   +1 more source

Inhibiting the oligomerization of mycobacterial DNA-directed RNA polymerase (RNAP) using natural compound via in-silico techniques

Ehssan Moglad
openalex   +1 more source